Factors predicting incidence of post-operative delirium in older people following hip fracture surgery: a systematic review and meta-analysis.

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Title: Factors predicting incidence of post-operative delirium in older people following hip fracture surgery: a systematic review and meta-analysis.
Authors: Smith, T. O., Cooper, A., Peryer, G., Griffiths, R., Fox, C., Cross, J.
Source: International Journal of Geriatric Psychiatry. Apr2017, Vol. 32 Issue 4, p386-396. 11p.
Subjects: Delirium, Fracture fixation complications, Treatment of fractures, Medical care, Pelvic fractures
Abstract: Objective: Delirium is one of the most common complications following hip fracture surgery in older people. This study identified pre- and peri-operative factors associated with the development of post-operative delirium following hip fracture surgery.Methods: Published and unpublished literature were searched to identify all evidence reporting variables on patient characteristics, on-admission, intra-operative and post-operative management assessing incident delirium in older people following hip fracture surgery. Pooled odds ratio (OR) and mean difference of those who experienced delirium compared to those who did not were calculated for each variable. Evidence was assessed using the Downs and Black appraisal tool and interpreted using the GRADE approach.Results: A total of 6704 people (2090 people with post-operative delirium) from 32 studies were analysed. There was moderate evidence of nearly a two-times greater probability of post-operative delirium for those aged 80 years and over (OR: 1.77; 95% CI: 1.09, 2.87), whether patients lived in a care institution pre-admission (OR: 2.65; 95% CI: 1.79, 3.92), and a six-times greater probability of developing post-operative delirium with a pre-admission diagnosis of dementia (OR: 6.07, 95% CI: 4.84, 7.62). There was no association with intra-operative variables and probability of delirium.Conclusion: Clinicians treating people with a hip fracture should be vigilant towards post-operative delirium if their patients are older, have pre-existing cognitive impairment and poorer overall general health. This is also the case for those who experience post-operative complications such as pneumonia or a urinary tract infection. Copyright © 2017 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Geriatric Psychiatry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Factors predicting incidence of post-operative delirium in older people following hip fracture surgery: a systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AR" term="%22Smith%2C+T%2E+O%2E%22">Smith, T. O.</searchLink><br /><searchLink fieldCode="AR" term="%22Cooper%2C+A%2E%22">Cooper, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Peryer%2C+G%2E%22">Peryer, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Griffiths%2C+R%2E%22">Griffiths, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Fox%2C+C%2E%22">Fox, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Cross%2C+J%2E%22">Cross, J.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Geriatric+Psychiatry%22">International Journal of Geriatric Psychiatry</searchLink>. Apr2017, Vol. 32 Issue 4, p386-396. 11p.
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  Data: <searchLink fieldCode="DE" term="%22Delirium%22">Delirium</searchLink><br /><searchLink fieldCode="DE" term="%22Fracture+fixation+complications%22">Fracture fixation complications</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+of+fractures%22">Treatment of fractures</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+care%22">Medical care</searchLink><br /><searchLink fieldCode="DE" term="%22Pelvic+fractures%22">Pelvic fractures</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: <bold>Objective: </bold>Delirium is one of the most common complications following hip fracture surgery in older people. This study identified pre- and peri-operative factors associated with the development of post-operative delirium following hip fracture surgery.<bold>Methods: </bold>Published and unpublished literature were searched to identify all evidence reporting variables on patient characteristics, on-admission, intra-operative and post-operative management assessing incident delirium in older people following hip fracture surgery. Pooled odds ratio (OR) and mean difference of those who experienced delirium compared to those who did not were calculated for each variable. Evidence was assessed using the Downs and Black appraisal tool and interpreted using the GRADE approach.<bold>Results: </bold>A total of 6704 people (2090 people with post-operative delirium) from 32 studies were analysed. There was moderate evidence of nearly a two-times greater probability of post-operative delirium for those aged 80 years and over (OR: 1.77; 95% CI: 1.09, 2.87), whether patients lived in a care institution pre-admission (OR: 2.65; 95% CI: 1.79, 3.92), and a six-times greater probability of developing post-operative delirium with a pre-admission diagnosis of dementia (OR: 6.07, 95% CI: 4.84, 7.62). There was no association with intra-operative variables and probability of delirium.<bold>Conclusion: </bold>Clinicians treating people with a hip fracture should be vigilant towards post-operative delirium if their patients are older, have pre-existing cognitive impairment and poorer overall general health. This is also the case for those who experience post-operative complications such as pneumonia or a urinary tract infection. Copyright © 2017 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
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  Group: Ab
  Data: <i>Copyright of International Journal of Geriatric Psychiatry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Text: English
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        Type: general
      – SubjectFull: Fracture fixation complications
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      – SubjectFull: Treatment of fractures
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              Text: Apr2017
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