PSYCHONEUROIMMUNOLOGY AND THE COURSE OF BREAST CANCER: AN OVERVIEW.

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Title: PSYCHONEUROIMMUNOLOGY AND THE COURSE OF BREAST CANCER: AN OVERVIEW.
Authors: van der Pompe, G., Antoni, M. H., Mulder, C. L., Heijnen, C., Goodkin, K., de Graeff, A., Garssen, B., de Vries, M. J.
Source: Psycho-Oncology. Dec1994, Vol. 3 Issue 4, p271-288. 18p.
Subjects: Psychoneuroimmunology, Breast cancer, Endocrine glands, Immune system, Tumor growth, Neuroimmunology
Abstract: This review focuses upon possible mediators of the frequently noted associations between psychosocial factors and the progression of breast cancer. First, host-related endocrine and immunological processes that may play an important role in the carcinogenesis and progression of breast cancer are summarized. Second, the effects of several endocrines on different components of the immune system that have been shown to be related to the course of breast cancer are addressed. Third, studies examining the effect of psychosocial factors on immune function conducted with breast cancer patients and healthy individuals are described. Based on this review, it can be concluded that causal relations between psychosocial stressors, endocrine and immune processes, and breast cancer progression remain to be elucidated. It can be hypothesized that psychosocial stressors influence the course of breast cancer by modulating endocrine processes which are directly related to tumor growth or indirectly related by decreasing immunologic control over tumor development and metastases. Finally, methodological pitfalls that plague this line of research are summarized and recommendations for future psychoneuroimmunologic research in breast cancer are provided. [ABSTRACT FROM AUTHOR]
Copyright of Psycho-Oncology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: PSYCHONEUROIMMUNOLOGY AND THE COURSE OF BREAST CANCER: AN OVERVIEW.
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  Data: <searchLink fieldCode="JN" term="%22Psycho-Oncology%22">Psycho-Oncology</searchLink>. Dec1994, Vol. 3 Issue 4, p271-288. 18p.
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  Data: <searchLink fieldCode="DE" term="%22Psychoneuroimmunology%22">Psychoneuroimmunology</searchLink><br /><searchLink fieldCode="DE" term="%22Breast+cancer%22">Breast cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Endocrine+glands%22">Endocrine glands</searchLink><br /><searchLink fieldCode="DE" term="%22Immune+system%22">Immune system</searchLink><br /><searchLink fieldCode="DE" term="%22Tumor+growth%22">Tumor growth</searchLink><br /><searchLink fieldCode="DE" term="%22Neuroimmunology%22">Neuroimmunology</searchLink>
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  Label: Abstract
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  Data: This review focuses upon possible mediators of the frequently noted associations between psychosocial factors and the progression of breast cancer. First, host-related endocrine and immunological processes that may play an important role in the carcinogenesis and progression of breast cancer are summarized. Second, the effects of several endocrines on different components of the immune system that have been shown to be related to the course of breast cancer are addressed. Third, studies examining the effect of psychosocial factors on immune function conducted with breast cancer patients and healthy individuals are described. Based on this review, it can be concluded that causal relations between psychosocial stressors, endocrine and immune processes, and breast cancer progression remain to be elucidated. It can be hypothesized that psychosocial stressors influence the course of breast cancer by modulating endocrine processes which are directly related to tumor growth or indirectly related by decreasing immunologic control over tumor development and metastases. Finally, methodological pitfalls that plague this line of research are summarized and recommendations for future psychoneuroimmunologic research in breast cancer are provided. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Psycho-Oncology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1002/pon.2960030404
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      – SubjectFull: Psychoneuroimmunology
        Type: general
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      – SubjectFull: Endocrine glands
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      – SubjectFull: Immune system
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      – SubjectFull: Tumor growth
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              M: 12
              Text: Dec1994
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              Y: 1994
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