Longitudinal change of quality of life in the first five years of survival among disease-free Chinese breast cancer survivors.
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| Title: | Longitudinal change of quality of life in the first five years of survival among disease-free Chinese breast cancer survivors. |
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| Authors: | Lei, Yuan-Yuan (AUTHOR), Ho, Suzanne C. (AUTHOR), Lau, Thomas K. H. (AUTHOR), Kwok, Carol (AUTHOR), Cheng, Ashley (AUTHOR), Cheung, Ka Li (AUTHOR), Lee, Roselle (AUTHOR), Yeo, Winnie (AUTHOR) |
| Source: | Quality of Life Research. Jun2021, Vol. 30 Issue 6, p1583-1594. 12p. 3 Charts, 1 Graph. |
| Subjects: | Breast cancer, Progression-free survival, Quality of life, Cancer survivors, Physical mobility |
| Abstract: | Purpose: This study aimed to investigate changes of QoL during the first 5 years of survival among disease-free Chinese breast cancer survivors. Methods: A prospective cohort study enrolled 1462 Chinese women with early-stage breast cancer, and longitudinally visited those patients at four time-points, namely baseline (T0), 18- (T1), 36- (T2), and 60-month (T3) after diagnosis. This study included 992 patients who were disease-free during the first 5 years of survival and who had completed QoL assessments at all four time-points. Results: The score of global health status/QoL improved gradually (T1, T2, T3 > T0; P < 0.001 for overall comparisons). Social functioning score significantly improved when compared to that of T0 (T1, T2, T3 > T0; P < 0.001 for overall comparisons). In contrast, cognitive functioning score decreased (T0 > T1, T2, T3; P < 0.001 for overall comparisons). Scores of physical functioning, role functioning and emotional functioning showed a fluctuated picture, with the highest score achieved at T1. In symptoms profile, most of them scored lowest at T1 (best QoL). Multivariate analysis showed that several characteristics significantly correlated to changes in QoL from T0 to T3. For instance, patients with higher education had better recovery of physical functioning, role functioning, and social functioning. Conclusion: During the first 5 years of survival, patients' global health status/QoL improved over time, social functioning consistently improved, but cognitive functioning steadily deteriorated. Most of functioning domains and symptoms improved at 18-month follow-up, but such improvements were not maintained and even deteriorated at 36- and 60-month post-diagnosis. This study suggested that some interventions should be investigated during such period. [ABSTRACT FROM AUTHOR] |
| Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 150691901 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Longitudinal change of quality of life in the first five years of survival among disease-free Chinese breast cancer survivors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Lei%2C+Yuan-Yuan%22">Lei, Yuan-Yuan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ho%2C+Suzanne+C%2E%22">Ho, Suzanne C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lau%2C+Thomas+K%2E+H%2E%22">Lau, Thomas K. H.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kwok%2C+Carol%22">Kwok, Carol</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cheng%2C+Ashley%22">Cheng, Ashley</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cheung%2C+Ka+Li%22">Cheung, Ka Li</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lee%2C+Roselle%22">Lee, Roselle</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yeo%2C+Winnie%22">Yeo, Winnie</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Quality+of+Life+Research%22">Quality of Life Research</searchLink>. Jun2021, Vol. 30 Issue 6, p1583-1594. 12p. 3 Charts, 1 Graph. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Breast+cancer%22">Breast cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Progression-free+survival%22">Progression-free survival</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+survivors%22">Cancer survivors</searchLink><br /><searchLink fieldCode="DE" term="%22Physical+mobility%22">Physical mobility</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: This study aimed to investigate changes of QoL during the first 5 years of survival among disease-free Chinese breast cancer survivors. Methods: A prospective cohort study enrolled 1462 Chinese women with early-stage breast cancer, and longitudinally visited those patients at four time-points, namely baseline (T0), 18- (T1), 36- (T2), and 60-month (T3) after diagnosis. This study included 992 patients who were disease-free during the first 5 years of survival and who had completed QoL assessments at all four time-points. Results: The score of global health status/QoL improved gradually (T1, T2, T3 > T0; P < 0.001 for overall comparisons). Social functioning score significantly improved when compared to that of T0 (T1, T2, T3 > T0; P < 0.001 for overall comparisons). In contrast, cognitive functioning score decreased (T0 > T1, T2, T3; P < 0.001 for overall comparisons). Scores of physical functioning, role functioning and emotional functioning showed a fluctuated picture, with the highest score achieved at T1. In symptoms profile, most of them scored lowest at T1 (best QoL). Multivariate analysis showed that several characteristics significantly correlated to changes in QoL from T0 to T3. For instance, patients with higher education had better recovery of physical functioning, role functioning, and social functioning. Conclusion: During the first 5 years of survival, patients' global health status/QoL improved over time, social functioning consistently improved, but cognitive functioning steadily deteriorated. Most of functioning domains and symptoms improved at 18-month follow-up, but such improvements were not maintained and even deteriorated at 36- and 60-month post-diagnosis. This study suggested that some interventions should be investigated during such period. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s11136-020-02729-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 1583 Subjects: – SubjectFull: Breast cancer Type: general – SubjectFull: Progression-free survival Type: general – SubjectFull: Quality of life Type: general – SubjectFull: Cancer survivors Type: general – SubjectFull: Physical mobility Type: general Titles: – TitleFull: Longitudinal change of quality of life in the first five years of survival among disease-free Chinese breast cancer survivors. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lei, Yuan-Yuan – PersonEntity: Name: NameFull: Ho, Suzanne C. – PersonEntity: Name: NameFull: Lau, Thomas K. H. – PersonEntity: Name: NameFull: Kwok, Carol – PersonEntity: Name: NameFull: Cheng, Ashley – PersonEntity: Name: NameFull: Cheung, Ka Li – PersonEntity: Name: NameFull: Lee, Roselle – PersonEntity: Name: NameFull: Yeo, Winnie IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2021 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 09629343 Numbering: – Type: volume Value: 30 – Type: issue Value: 6 Titles: – TitleFull: Quality of Life Research Type: main |
| ResultId | 1 |
