View in EDS

The reduced left hippocampal volume related to the delayed P300 latency in amnestic mild cognitive impairment.

Saved in:
Bibliographic Details
Title: The reduced left hippocampal volume related to the delayed P300 latency in amnestic mild cognitive impairment.
Authors: Gao, Lijuan, Gu, Lihua, Shu, Hao, Chen, Jiu, Zhu, Jianli, Wang, Bi, Shi, Yachen, Song, Ruize, Li, Kun, Li, Xianrui, Zhang, Haisan, Zhang, Hongxing, Zhang, Zhijun
Source: Psychological Medicine. Sep2021, Vol. 51 Issue 12, p2054-2062. 9p.
Subjects: Cognition disorders, Evoked potentials (Electrophysiology), Gray matter (Nerve tissue), Parietal lobe, Hippocampus (Brain), Electroencephalography, Case-control method, Magnetic resonance imaging, Cerebral cortex anatomy, Neuropsychological tests, Amnesia
Abstract: Background: Amnestic mild cognitive impairment (aMCI) is characterized by delayed P300 latency and reduced grey matter (GM) volume, respectively. The relationship between the features in aMCI is unclear. This study was to investigate the relationship between the altered P300 latency and the GM volume in aMCI. Methods: Thirty-four aMCI and 34 well-matched normal controls (NC) were studied using electroencephalogram during a visual oddball task and scanned with MRI. Both tests were finished in the same day. Results: As compared with the NC group, the aMCI group exhibited delayed P300 latency in parietal cortex and reduced GM volumes in bilateral temporal pole and left hippocampus/parahippocampal gyrus. A remarkable negative correlation was found between delayed P300 latency and reduced left hippocampal volume only in the aMCI group. Interestingly, the mediating analysis found P300 latency significantly mediated the association between right supramarginal gyrus volume and information processing speed indicated by Stroop Color and Word Test A scores. Conclusions: The association between delayed P300 latency and reduced left hippocampal volume in aMCI subjects suggests that reduced left hippocampal volume may be the potential structural basis of delayed P300 latency. [ABSTRACT FROM AUTHOR]
Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 153538033
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The reduced left hippocampal volume related to the delayed P300 latency in amnestic mild cognitive impairment.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Gao%2C+Lijuan%22">Gao, Lijuan</searchLink><br /><searchLink fieldCode="AR" term="%22Gu%2C+Lihua%22">Gu, Lihua</searchLink><br /><searchLink fieldCode="AR" term="%22Shu%2C+Hao%22">Shu, Hao</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Jiu%22">Chen, Jiu</searchLink><br /><searchLink fieldCode="AR" term="%22Zhu%2C+Jianli%22">Zhu, Jianli</searchLink><br /><searchLink fieldCode="AR" term="%22Wang%2C+Bi%22">Wang, Bi</searchLink><br /><searchLink fieldCode="AR" term="%22Shi%2C+Yachen%22">Shi, Yachen</searchLink><br /><searchLink fieldCode="AR" term="%22Song%2C+Ruize%22">Song, Ruize</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Kun%22">Li, Kun</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Xianrui%22">Li, Xianrui</searchLink><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Haisan%22">Zhang, Haisan</searchLink><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Hongxing%22">Zhang, Hongxing</searchLink><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Zhijun%22">Zhang, Zhijun</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Psychological+Medicine%22">Psychological Medicine</searchLink>. Sep2021, Vol. 51 Issue 12, p2054-2062. 9p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Cognition+disorders%22">Cognition disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Evoked+potentials+%28Electrophysiology%29%22">Evoked potentials (Electrophysiology)</searchLink><br /><searchLink fieldCode="DE" term="%22Gray+matter+%28Nerve+tissue%29%22">Gray matter (Nerve tissue)</searchLink><br /><searchLink fieldCode="DE" term="%22Parietal+lobe%22">Parietal lobe</searchLink><br /><searchLink fieldCode="DE" term="%22Hippocampus+%28Brain%29%22">Hippocampus (Brain)</searchLink><br /><searchLink fieldCode="DE" term="%22Electroencephalography%22">Electroencephalography</searchLink><br /><searchLink fieldCode="DE" term="%22Case-control+method%22">Case-control method</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebral+cortex+anatomy%22">Cerebral cortex anatomy</searchLink><br /><searchLink fieldCode="DE" term="%22Neuropsychological+tests%22">Neuropsychological tests</searchLink><br /><searchLink fieldCode="DE" term="%22Amnesia%22">Amnesia</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Amnestic mild cognitive impairment (aMCI) is characterized by delayed P300 latency and reduced grey matter (GM) volume, respectively. The relationship between the features in aMCI is unclear. This study was to investigate the relationship between the altered P300 latency and the GM volume in aMCI. Methods: Thirty-four aMCI and 34 well-matched normal controls (NC) were studied using electroencephalogram during a visual oddball task and scanned with MRI. Both tests were finished in the same day. Results: As compared with the NC group, the aMCI group exhibited delayed P300 latency in parietal cortex and reduced GM volumes in bilateral temporal pole and left hippocampus/parahippocampal gyrus. A remarkable negative correlation was found between delayed P300 latency and reduced left hippocampal volume only in the aMCI group. Interestingly, the mediating analysis found P300 latency significantly mediated the association between right supramarginal gyrus volume and information processing speed indicated by Stroop Color and Word Test A scores. Conclusions: The association between delayed P300 latency and reduced left hippocampal volume in aMCI subjects suggests that reduced left hippocampal volume may be the potential structural basis of delayed P300 latency. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=153538033
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1017/S0033291720000811
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 2054
    Subjects:
      – SubjectFull: Cognition disorders
        Type: general
      – SubjectFull: Evoked potentials (Electrophysiology)
        Type: general
      – SubjectFull: Gray matter (Nerve tissue)
        Type: general
      – SubjectFull: Parietal lobe
        Type: general
      – SubjectFull: Hippocampus (Brain)
        Type: general
      – SubjectFull: Electroencephalography
        Type: general
      – SubjectFull: Case-control method
        Type: general
      – SubjectFull: Magnetic resonance imaging
        Type: general
      – SubjectFull: Cerebral cortex anatomy
        Type: general
      – SubjectFull: Neuropsychological tests
        Type: general
      – SubjectFull: Amnesia
        Type: general
    Titles:
      – TitleFull: The reduced left hippocampal volume related to the delayed P300 latency in amnestic mild cognitive impairment.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Gao, Lijuan
      – PersonEntity:
          Name:
            NameFull: Gu, Lihua
      – PersonEntity:
          Name:
            NameFull: Shu, Hao
      – PersonEntity:
          Name:
            NameFull: Chen, Jiu
      – PersonEntity:
          Name:
            NameFull: Zhu, Jianli
      – PersonEntity:
          Name:
            NameFull: Wang, Bi
      – PersonEntity:
          Name:
            NameFull: Shi, Yachen
      – PersonEntity:
          Name:
            NameFull: Song, Ruize
      – PersonEntity:
          Name:
            NameFull: Li, Kun
      – PersonEntity:
          Name:
            NameFull: Li, Xianrui
      – PersonEntity:
          Name:
            NameFull: Zhang, Haisan
      – PersonEntity:
          Name:
            NameFull: Zhang, Hongxing
      – PersonEntity:
          Name:
            NameFull: Zhang, Zhijun
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: Sep2021
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 00332917
          Numbering:
            – Type: volume
              Value: 51
            – Type: issue
              Value: 12
          Titles:
            – TitleFull: Psychological Medicine
              Type: main
ResultId 1