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Early Adverse Experiences and Repeated Wheezing From 6 to 30 Months of Age: Investigating the Roles of Hypothalamic–Pituitary–Adrenal Axis Functioning, Child Sex, and Caregiving Sensitivity.

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Title: Early Adverse Experiences and Repeated Wheezing From 6 to 30 Months of Age: Investigating the Roles of Hypothalamic–Pituitary–Adrenal Axis Functioning, Child Sex, and Caregiving Sensitivity.
Authors: Frost, Allison (AUTHOR), Bosquet Enlow, Michelle (AUTHOR), Malin, Ashley J. (AUTHOR), Bernard, Kristin (AUTHOR), Wright, Rosalind J. (AUTHOR)
Source: Child Development. Nov/Dec2021, Vol. 92 Issue 6, pe1260-e1274. 15p. 5 Charts, 2 Graphs.
Subjects: Adverse childhood experiences, Wheeze, Adrenal glands, Caregivers, Anxiety sensitivity, Mother-child relationship, Minorities, Circadian rhythms
Abstract: This study examined associations among early adversity, diurnal cortisol, child sex, and caregiver sensitivity at age 6 months in relation to wheezing in children (47% male) followed to 30 months. Analyses included 676 mother‐child dyads, 393 of whom completed an observational caregiver sensitivity measure. Participants were primarily ethnic minorities (42.7% Black, 25.4% Hispanic); 22.1% of children had ≥ 1 wheezing episode. Higher adversity was associated with increased wheeze frequency and blunted diurnal cortisol slope. The indirect effect of adversity on wheezing through cortisol slope was significant for females, but not males. Higher caregiver sensitivity was protective against wheezing for males, but not females, with high cortisol. Findings suggest complex associations among adversity, cortisol, child sex, and caregiver sensitivity in predicting wheezing. [ABSTRACT FROM AUTHOR]
Copyright of Child Development is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Early Adverse Experiences and Repeated Wheezing From 6 to 30 Months of Age: Investigating the Roles of Hypothalamic–Pituitary–Adrenal Axis Functioning, Child Sex, and Caregiving Sensitivity.
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  Data: <searchLink fieldCode="JN" term="%22Child+Development%22">Child Development</searchLink>. Nov/Dec2021, Vol. 92 Issue 6, pe1260-e1274. 15p. 5 Charts, 2 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Adverse+childhood+experiences%22">Adverse childhood experiences</searchLink><br /><searchLink fieldCode="DE" term="%22Wheeze%22">Wheeze</searchLink><br /><searchLink fieldCode="DE" term="%22Adrenal+glands%22">Adrenal glands</searchLink><br /><searchLink fieldCode="DE" term="%22Caregivers%22">Caregivers</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety+sensitivity%22">Anxiety sensitivity</searchLink><br /><searchLink fieldCode="DE" term="%22Mother-child+relationship%22">Mother-child relationship</searchLink><br /><searchLink fieldCode="DE" term="%22Minorities%22">Minorities</searchLink><br /><searchLink fieldCode="DE" term="%22Circadian+rhythms%22">Circadian rhythms</searchLink>
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  Data: This study examined associations among early adversity, diurnal cortisol, child sex, and caregiver sensitivity at age 6 months in relation to wheezing in children (47% male) followed to 30 months. Analyses included 676 mother‐child dyads, 393 of whom completed an observational caregiver sensitivity measure. Participants were primarily ethnic minorities (42.7% Black, 25.4% Hispanic); 22.1% of children had ≥ 1 wheezing episode. Higher adversity was associated with increased wheeze frequency and blunted diurnal cortisol slope. The indirect effect of adversity on wheezing through cortisol slope was significant for females, but not males. Higher caregiver sensitivity was protective against wheezing for males, but not females, with high cortisol. Findings suggest complex associations among adversity, cortisol, child sex, and caregiver sensitivity in predicting wheezing. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Child Development is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1111/cdev.13606
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        Text: English
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      – SubjectFull: Adverse childhood experiences
        Type: general
      – SubjectFull: Wheeze
        Type: general
      – SubjectFull: Adrenal glands
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      – SubjectFull: Caregivers
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      – SubjectFull: Anxiety sensitivity
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      – SubjectFull: Mother-child relationship
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      – SubjectFull: Minorities
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      – SubjectFull: Circadian rhythms
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      – TitleFull: Early Adverse Experiences and Repeated Wheezing From 6 to 30 Months of Age: Investigating the Roles of Hypothalamic–Pituitary–Adrenal Axis Functioning, Child Sex, and Caregiving Sensitivity.
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              M: 11
              Text: Nov/Dec2021
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              Y: 2021
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