The importance of suicide risk assessment in patients affected by neurofibromatosis.
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| Title: | The importance of suicide risk assessment in patients affected by neurofibromatosis. |
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| Authors: | Berardelli, Isabella, Maraone, Annalisa, Belvisi, Daniele, Pasquini, Massimo, Giustini, Sandra, Miraglia, Emanuele, Iacovino, Chiara, Pompili, Maurizio, Frascarelli, Marianna, Fabbrini, Giovanni |
| Source: | International Journal of Psychiatry in Clinical Practice. Nov 2021, Vol. 25 Issue 4, p350-355. 6p. |
| Subjects: | Multiple regression analysis, Beck Hopelessness Scale, Suicidal ideation, Risk assessment, Despair, Mental depression, Descriptive statistics, Neurofibromatosis, People with disabilities, Classification of mental disorders, Mental illness, Disease complications |
| Geographic Terms: | Italy |
| Abstract: | Neurofibromatosis 1 (NF1) is a chronic medical disease that often presents with psychiatric disorders. We investigated suicidal ideation in NF1 patients compared to healthy controls. We also evaluated whether hopelessness, depressive symptoms and perceived disability may mediate suicidal ideation in patients with NF1. We enrolled 60 patients with NF1 and 50 healthy controls with no history of NF1. Patients underwent a full psychiatric evaluation. Psychiatric diagnosis was made according to Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) criteria. Patients and controls underwent a series of psychometric measures, namely the Columbia Suicide Severity Rating Scale, the Beck Hopelessness Scale, the Italian Perceived Disability Scale and the Beck Depression Inventory. Suicidal ideation was significantly higher in patients with NF1 (45%) than in controls (10%). Patients also presented more severe perceived disability and hopelessness and more frequent psychiatric disorders than controls. Multivariable logistic regression analysis showed that perceived disability was independently associated with the presence of suicidal ideation in patients with NF1. In conclusion, our results showed that suicidal ideation was present in almost half of patients with NF1, suggesting the importance of suicide assessment in these patients. Patients with NF1 have an increased suicide ideation when compared to healthy controls Increased suicidal ideation correlates with perceived disability, but not with the presence of psychiatric disorders Assessment of suicidal ideation should be performed in patients with NF1 [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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