Massive cerebral venous sinus thrombosis in vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCoV-19 serum: case report of a successful multidisciplinary approach.

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Title: Massive cerebral venous sinus thrombosis in vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCoV-19 serum: case report of a successful multidisciplinary approach.
Authors: Mirandola, Laura (AUTHOR), Arena, Giulia (AUTHOR), Pagliaro, Maria (AUTHOR), Boghi, Andrea (AUTHOR), Naldi, Andrea (AUTHOR), Castellano, Davide (AUTHOR), Vaccarino, Antonella (AUTHOR), Silengo, Daniela (AUTHOR), Aprà, Franco (AUTHOR), Cavallo, Roberto (AUTHOR), Livigni, Sergio (AUTHOR)
Source: Neurological Sciences. Mar2022, Vol. 43 Issue 3, p1499-1502. 4p.
Subjects: Sinus thrombosis, Thrombectomy, Neurosurgery, Interdisciplinary research, Endovascular surgery, COVID-19 vaccines, Emergency medicine, Vaccination complications
Abstract: We report a case of massive cerebral venous sinus thrombosis in the contest of vaccine-induced immune thrombotic thrombocytopenia that required the rapid coordination of many specialists from different departments, notably emergency, neurology, neuroradiology, hematology, and neurosurgery. The patient was rapidly treated with steroids, immunoglobulin, and fondaparinux. She underwent within 6 h after hospital admission a mechanical thrombectomy in order to allow flow restoration in cerebral venous systems. Neuroendovascular treatment in cerebral venous thrombosis related to VITT has never been described before. It can represent a complementary tool along with the other therapies and a multidisciplinary approach. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Massive cerebral venous sinus thrombosis in vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCoV-19 serum: case report of a successful multidisciplinary approach.
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  Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. Mar2022, Vol. 43 Issue 3, p1499-1502. 4p.
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  Data: <searchLink fieldCode="DE" term="%22Sinus+thrombosis%22">Sinus thrombosis</searchLink><br /><searchLink fieldCode="DE" term="%22Thrombectomy%22">Thrombectomy</searchLink><br /><searchLink fieldCode="DE" term="%22Neurosurgery%22">Neurosurgery</searchLink><br /><searchLink fieldCode="DE" term="%22Interdisciplinary+research%22">Interdisciplinary research</searchLink><br /><searchLink fieldCode="DE" term="%22Endovascular+surgery%22">Endovascular surgery</searchLink><br /><searchLink fieldCode="DE" term="%22COVID-19+vaccines%22">COVID-19 vaccines</searchLink><br /><searchLink fieldCode="DE" term="%22Emergency+medicine%22">Emergency medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Vaccination+complications%22">Vaccination complications</searchLink>
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  Data: We report a case of massive cerebral venous sinus thrombosis in the contest of vaccine-induced immune thrombotic thrombocytopenia that required the rapid coordination of many specialists from different departments, notably emergency, neurology, neuroradiology, hematology, and neurosurgery. The patient was rapidly treated with steroids, immunoglobulin, and fondaparinux. She underwent within 6 h after hospital admission a mechanical thrombectomy in order to allow flow restoration in cerebral venous systems. Neuroendovascular treatment in cerebral venous thrombosis related to VITT has never been described before. It can represent a complementary tool along with the other therapies and a multidisciplinary approach. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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              Text: Mar2022
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