Miller Fisher syndrome following COVID‐19 vaccines: A scoping review.

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Bibliographic Details
Title: Miller Fisher syndrome following COVID‐19 vaccines: A scoping review.
Authors: Kim, Jee‐Eun (AUTHOR), Yoon, Byeol‐A (AUTHOR), Kim, Yoo Hwan (AUTHOR), Kim, Jong Kuk (AUTHOR), Bae, Jong Seok (AUTHOR)
Source: Acta Neurologica Scandinavica. Nov2022, Vol. 146 Issue 5, p604-609. 6p.
Subjects: COVID-19 vaccines, COVID-19, Guillain-Barré syndrome, COVID-19 pandemic, Syndromes
Abstract: Background and Purpose: Miller Fisher syndrome (MFS), a variant of Guillain–Barré Syndrome (GBS), could be underestimated in evaluations of its adverse events (AEs) following COVID‐19 vaccination. We aimed to identify and characterize MFS following COVID‐19 vaccination. Materials and Methods: Relevant studies reported on during the COVID‐19 pandemic were identified in the MEDLINE, Embase, and other databases. Results: Nine cases of MFS following COVID‐19 vaccination from various regions were included. Unlike MFS following COVID‐19 infection, patients with MFS following COVID‐19 vaccination frequently presented with anti‐GQ1b antibody positivity (44%, 4/9). Unlike GBS following COVID‐19 vaccination, only two of nine (22%) cases of MFS following COVID‐19 vaccination had developed after viral‐vector‐related vaccine administration. Conclusions: Miller Fisher syndrome following COVID‐19 vaccination seems to have a different pathophysiology from MFS following COVID‐19 infection and GBS following COVID‐19 vaccination. This neurological syndrome with a rare incidence and difficulty in diagnosis should be considered an AE of COVID‐19 vaccination. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
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