Acceptability of the dapivirine vaginal ring for HIV-1 prevention among women reporting engagement in transactional sex.

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Title: Acceptability of the dapivirine vaginal ring for HIV-1 prevention among women reporting engagement in transactional sex.
Authors: Browne, Erica N., Torjesen, Kristine, Mirembe, Brenda Gati, Palanee-Phillips, Thesla, Jeenarain, Nitesha, Chitukuta, Miria, Stoner, Marie C. D., Mansoor, Leila E., Reddy, Krishnaveni, Tauya, Thelma T., Naidoo, Logashvari, Siva, Samantha, Richardson, Barbra, Dadabhai, Sufia, Seyama, Linly, Soto-Torres, Lydia, van der Straten, Ariane
Source: AIDS Care. Jan2024, Vol. 36 Issue 1, p80-86. 7p.
Subjects: HIV prevention, Confidence intervals, Counseling, Social support, Transactional sex, Comparative studies, Descriptive statistics, Research funding, Cervical caps, Odds ratio, HIV, Women's health, Poisson distribution
Abstract: We assessed if acceptability of the dapivirine vaginal ring for HIV prevention differed among the subgroup of women who reported engaging in transactional sex prior to enrollment in MTN-020/ASPIRE (phase III trial in Malawi, South Africa, Uganda, and Zimbabwe, 2012-2015; n = 2629). Transactional sex was defined as receipt of money, goods, gifts, drugs, or shelter in exchange for sex in the past year. Dimensions of acceptability included: ease of use and physical sensation in situ, impacts on sex, partner's opinion, and likelihood of future use. We used Poisson regression models with robust standard errors to compare risk of acceptability challenges by baseline history of transactional sex. At product discontinuation, women exchanging sex found the ring comfortable (90%), easy to insert (92%) and nearly all (96%) were likely to use the ring in the future. Women who had exchanged sex were more likely to report feeling the ring during sex (ARR 1.43, 95% CI: 1.09, 1.89; p = 0.01) and slightly more likely to mind wearing the ring during menses (ARR 1.22, 95% CI: 1.01, 1,46; p = 0.04) and during sex (ARR 1.22, 95% CI: 1.02, 1.45; p = 0.03). Messaging and counseling should include enhanced support for use during sex and menses to support optimal use. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Acceptability of the dapivirine vaginal ring for HIV-1 prevention among women reporting engagement in transactional sex.
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  Data: <searchLink fieldCode="AR" term="%22Browne%2C+Erica+N%2E%22">Browne, Erica N.</searchLink><br /><searchLink fieldCode="AR" term="%22Torjesen%2C+Kristine%22">Torjesen, Kristine</searchLink><br /><searchLink fieldCode="AR" term="%22Mirembe%2C+Brenda+Gati%22">Mirembe, Brenda Gati</searchLink><br /><searchLink fieldCode="AR" term="%22Palanee-Phillips%2C+Thesla%22">Palanee-Phillips, Thesla</searchLink><br /><searchLink fieldCode="AR" term="%22Jeenarain%2C+Nitesha%22">Jeenarain, Nitesha</searchLink><br /><searchLink fieldCode="AR" term="%22Chitukuta%2C+Miria%22">Chitukuta, Miria</searchLink><br /><searchLink fieldCode="AR" term="%22Stoner%2C+Marie+C%2E+D%2E%22">Stoner, Marie C. D.</searchLink><br /><searchLink fieldCode="AR" term="%22Mansoor%2C+Leila+E%2E%22">Mansoor, Leila E.</searchLink><br /><searchLink fieldCode="AR" term="%22Reddy%2C+Krishnaveni%22">Reddy, Krishnaveni</searchLink><br /><searchLink fieldCode="AR" term="%22Tauya%2C+Thelma+T%2E%22">Tauya, Thelma T.</searchLink><br /><searchLink fieldCode="AR" term="%22Naidoo%2C+Logashvari%22">Naidoo, Logashvari</searchLink><br /><searchLink fieldCode="AR" term="%22Siva%2C+Samantha%22">Siva, Samantha</searchLink><br /><searchLink fieldCode="AR" term="%22Richardson%2C+Barbra%22">Richardson, Barbra</searchLink><br /><searchLink fieldCode="AR" term="%22Dadabhai%2C+Sufia%22">Dadabhai, Sufia</searchLink><br /><searchLink fieldCode="AR" term="%22Seyama%2C+Linly%22">Seyama, Linly</searchLink><br /><searchLink fieldCode="AR" term="%22Soto-Torres%2C+Lydia%22">Soto-Torres, Lydia</searchLink><br /><searchLink fieldCode="AR" term="%22van+der+Straten%2C+Ariane%22">van der Straten, Ariane</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Jan2024, Vol. 36 Issue 1, p80-86. 7p.
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  Data: <searchLink fieldCode="DE" term="%22HIV+prevention%22">HIV prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Counseling%22">Counseling</searchLink><br /><searchLink fieldCode="DE" term="%22Social+support%22">Social support</searchLink><br /><searchLink fieldCode="DE" term="%22Transactional+sex%22">Transactional sex</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Cervical+caps%22">Cervical caps</searchLink><br /><searchLink fieldCode="DE" term="%22Odds+ratio%22">Odds ratio</searchLink><br /><searchLink fieldCode="DE" term="%22HIV%22">HIV</searchLink><br /><searchLink fieldCode="DE" term="%22Women's+health%22">Women's health</searchLink><br /><searchLink fieldCode="DE" term="%22Poisson+distribution%22">Poisson distribution</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: We assessed if acceptability of the dapivirine vaginal ring for HIV prevention differed among the subgroup of women who reported engaging in transactional sex prior to enrollment in MTN-020/ASPIRE (phase III trial in Malawi, South Africa, Uganda, and Zimbabwe, 2012-2015; n = 2629). Transactional sex was defined as receipt of money, goods, gifts, drugs, or shelter in exchange for sex in the past year. Dimensions of acceptability included: ease of use and physical sensation in situ, impacts on sex, partner's opinion, and likelihood of future use. We used Poisson regression models with robust standard errors to compare risk of acceptability challenges by baseline history of transactional sex. At product discontinuation, women exchanging sex found the ring comfortable (90%), easy to insert (92%) and nearly all (96%) were likely to use the ring in the future. Women who had exchanged sex were more likely to report feeling the ring during sex (ARR 1.43, 95% CI: 1.09, 1.89; p = 0.01) and slightly more likely to mind wearing the ring during menses (ARR 1.22, 95% CI: 1.01, 1,46; p = 0.04) and during sex (ARR 1.22, 95% CI: 1.02, 1.45; p = 0.03). Messaging and counseling should include enhanced support for use during sex and menses to support optimal use. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2023.2198187
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      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 80
    Subjects:
      – SubjectFull: HIV prevention
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Counseling
        Type: general
      – SubjectFull: Social support
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      – SubjectFull: Transactional sex
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      – SubjectFull: Comparative studies
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      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Cervical caps
        Type: general
      – SubjectFull: Odds ratio
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      – SubjectFull: HIV
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      – SubjectFull: Women's health
        Type: general
      – SubjectFull: Poisson distribution
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      – TitleFull: Acceptability of the dapivirine vaginal ring for HIV-1 prevention among women reporting engagement in transactional sex.
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