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Facilitators of PrEP Persistence among Black and Latinx Transgender Women in a PrEP Demonstration Project in Southern California.

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Title: Facilitators of PrEP Persistence among Black and Latinx Transgender Women in a PrEP Demonstration Project in Southern California.
Authors: Storholm, Erik D., Ogunbajo, Adedotun, Nacht, Carrie L., Opalo, Chloe, Horvath, Keith J., Lyman, Phoebe, Flynn, Risa, Reback, Cathy J., Blumenthal, Jill, Moore, David J., Bolan, Robert, Morris, Sheldon
Source: Behavioral Medicine. Jan-Mar2024, Vol. 50 Issue 1, p63-74. 12p.
Subjects: HIV prevention, Black LGBTQ+ people, Hispanic Americans, Trans women, Tenofovir, Motivation (Psychology), Interviewing, Mental health, Pre-exposure prophylaxis, Qualitative research, Research funding, Drugs, Content analysis, Patient compliance, Health equity, Longitudinal method
Geographic Terms: California
Abstract: Black and Latinx transgender women in the United States (U.S.) are at disproportionately high risk for HIV. Although HIV pre-exposure prophylaxis (PrEP) reduces the risk of HIV infection, uptake and persistence (i.e., ability to continue taking PrEP over time) can be a challenge for Black and Latinx transgender women due to myriad social and structural forces. In this qualitative study, we present unique data on the facilitators of PrEP persistence from Black and Latinx transgender women who initiated PrEP and exhibited varying levels of persistence during a demonstration project in Southern California. PrEP persistence was assessed by collecting quantitative intracellular tenofovir-diphosphate (TFV-DP) levels on dried blood spot (DBS) samples collected at weeks 12 and 48. Informed by the socioecological framework, we conducted and analyzed interviews using qualitative content analysis to determine themes on the facilitators of PrEP persistence. Individual-level facilitators included the use of reminders, having high individual-level HIV risk perception, feeling empowered to take PrEP, and reporting having improved peace of mind and mental health because of taking PrEP. Interpersonal/Community-level facilitators included feeling motivation to prevent HIV in the community, motivation to prevent HIV in the context of sex work, and having high community-level risk perception. Structural-level facilitators included having positive experiences in affirming healthcare settings and having PrEP visits combined with other gender-related healthcare visits. Interventions aiming to increase PrEP uptake and persistence among Black and Latinx transgender women in the U.S. should harness the multiple levels of support exhibited by those who were able to start and persist on PrEP in the face of the myriad social and structural barriers. [ABSTRACT FROM AUTHOR]
Copyright of Behavioral Medicine is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Facilitators of PrEP Persistence among Black and Latinx Transgender Women in a PrEP Demonstration Project in Southern California.
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  Data: <searchLink fieldCode="AR" term="%22Storholm%2C+Erik+D%2E%22">Storholm, Erik D.</searchLink><br /><searchLink fieldCode="AR" term="%22Ogunbajo%2C+Adedotun%22">Ogunbajo, Adedotun</searchLink><br /><searchLink fieldCode="AR" term="%22Nacht%2C+Carrie+L%2E%22">Nacht, Carrie L.</searchLink><br /><searchLink fieldCode="AR" term="%22Opalo%2C+Chloe%22">Opalo, Chloe</searchLink><br /><searchLink fieldCode="AR" term="%22Horvath%2C+Keith+J%2E%22">Horvath, Keith J.</searchLink><br /><searchLink fieldCode="AR" term="%22Lyman%2C+Phoebe%22">Lyman, Phoebe</searchLink><br /><searchLink fieldCode="AR" term="%22Flynn%2C+Risa%22">Flynn, Risa</searchLink><br /><searchLink fieldCode="AR" term="%22Reback%2C+Cathy+J%2E%22">Reback, Cathy J.</searchLink><br /><searchLink fieldCode="AR" term="%22Blumenthal%2C+Jill%22">Blumenthal, Jill</searchLink><br /><searchLink fieldCode="AR" term="%22Moore%2C+David+J%2E%22">Moore, David J.</searchLink><br /><searchLink fieldCode="AR" term="%22Bolan%2C+Robert%22">Bolan, Robert</searchLink><br /><searchLink fieldCode="AR" term="%22Morris%2C+Sheldon%22">Morris, Sheldon</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Behavioral+Medicine%22">Behavioral Medicine</searchLink>. Jan-Mar2024, Vol. 50 Issue 1, p63-74. 12p.
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  Data: <searchLink fieldCode="DE" term="%22HIV+prevention%22">HIV prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Black+LGBTQ%2B+people%22">Black LGBTQ+ people</searchLink><br /><searchLink fieldCode="DE" term="%22Hispanic+Americans%22">Hispanic Americans</searchLink><br /><searchLink fieldCode="DE" term="%22Trans+women%22">Trans women</searchLink><br /><searchLink fieldCode="DE" term="%22Tenofovir%22">Tenofovir</searchLink><br /><searchLink fieldCode="DE" term="%22Motivation+%28Psychology%29%22">Motivation (Psychology)</searchLink><br /><searchLink fieldCode="DE" term="%22Interviewing%22">Interviewing</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+health%22">Mental health</searchLink><br /><searchLink fieldCode="DE" term="%22Pre-exposure+prophylaxis%22">Pre-exposure prophylaxis</searchLink><br /><searchLink fieldCode="DE" term="%22Qualitative+research%22">Qualitative research</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Drugs%22">Drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Content+analysis%22">Content analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Patient+compliance%22">Patient compliance</searchLink><br /><searchLink fieldCode="DE" term="%22Health+equity%22">Health equity</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22California%22">California</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Black and Latinx transgender women in the United States (U.S.) are at disproportionately high risk for HIV. Although HIV pre-exposure prophylaxis (PrEP) reduces the risk of HIV infection, uptake and persistence (i.e., ability to continue taking PrEP over time) can be a challenge for Black and Latinx transgender women due to myriad social and structural forces. In this qualitative study, we present unique data on the facilitators of PrEP persistence from Black and Latinx transgender women who initiated PrEP and exhibited varying levels of persistence during a demonstration project in Southern California. PrEP persistence was assessed by collecting quantitative intracellular tenofovir-diphosphate (TFV-DP) levels on dried blood spot (DBS) samples collected at weeks 12 and 48. Informed by the socioecological framework, we conducted and analyzed interviews using qualitative content analysis to determine themes on the facilitators of PrEP persistence. Individual-level facilitators included the use of reminders, having high individual-level HIV risk perception, feeling empowered to take PrEP, and reporting having improved peace of mind and mental health because of taking PrEP. Interpersonal/Community-level facilitators included feeling motivation to prevent HIV in the community, motivation to prevent HIV in the context of sex work, and having high community-level risk perception. Structural-level facilitators included having positive experiences in affirming healthcare settings and having PrEP visits combined with other gender-related healthcare visits. Interventions aiming to increase PrEP uptake and persistence among Black and Latinx transgender women in the U.S. should harness the multiple levels of support exhibited by those who were able to start and persist on PrEP in the face of the myriad social and structural barriers. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Behavioral Medicine is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1080/08964289.2022.2105794
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      – Code: eng
        Text: English
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    Subjects:
      – SubjectFull: HIV prevention
        Type: general
      – SubjectFull: Black LGBTQ+ people
        Type: general
      – SubjectFull: Hispanic Americans
        Type: general
      – SubjectFull: Trans women
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      – SubjectFull: Motivation (Psychology)
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      – SubjectFull: Research funding
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      – SubjectFull: Drugs
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      – SubjectFull: Patient compliance
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      – SubjectFull: Health equity
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      – SubjectFull: Longitudinal method
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      – SubjectFull: California
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      – TitleFull: Facilitators of PrEP Persistence among Black and Latinx Transgender Women in a PrEP Demonstration Project in Southern California.
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              Text: Jan-Mar2024
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