QI-TRAINING (QIGONG) ENHANCED IMMUNE FUNCTIONS: WHAT IS THE UNDERLYING MECHANISM?
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| Title: | QI-TRAINING (QIGONG) ENHANCED IMMUNE FUNCTIONS: WHAT IS THE UNDERLYING MECHANISM? |
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| Authors: | LEE, MYEONG SOO (AUTHOR), KIM, MO KYUNG (AUTHOR), RYU, HOON (AUTHOR) |
| Source: | International Journal of Neuroscience. Aug2005, Vol. 115 Issue 8, p1099-1104. 6p. |
| Subjects: | Qi gong, Neurohormones, Neutrophils, Somatotropin, Chinese medicine, Neurosciences |
| Abstract: | The authors observed that Qi-training enhances immune function and modulates neurohormone concentrations. The exact signal and priming mechanism for enhanced neutrophil function by Qi-training has not yet been demonstrated. This study investigated the effect of Qi-training on intracellular signaling leading to the enhancement of immune function. The growth hormone (GH) concentrations and O2- production by neutrophils (PMNs) was significantly increased after 1 h of Qi-training compared with the basal state. To verify that endogenous GH mediates the priming of PMNs, serum obtained from elderly subjects in the basal state and after Qi-training was incubated with neutrophils isolated from young subjects for 60 min and triggered with N-formyl-1-methionyl-1-leucyl- 1-phenylalanine (fMLP). Significant O2 - production was observed in the PMNs incubated with serum collected after a Qi-training (p < .05). On the other hand, the priming effect on the PMNs was abolished in Qi-training sera depleted of endogenous GH with anti-human GH polyclonal antibody (p < .01) and the tyrosine kinase inhibitor, genistein (p < .01). The authors suggest that the endogenous GH released during and immediately after Qi-training mediates the priming events through tyrosine kinase activation in PMNs. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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