View in EDS HTML Full Text PDF Full Text

Mortality of alzheimer's disease in Italy from 1980 to 2015.

Saved in:
Bibliographic Details
Title: Mortality of alzheimer's disease in Italy from 1980 to 2015.
Authors: Bezzini, Daiana (AUTHOR), Smeralda, Carmelo L. (AUTHOR), Pasqualetti, Patrizio (AUTHOR), Cappa, Stefano F. (AUTHOR), Kundisova, Lucia (AUTHOR), Rossi, Simone (AUTHOR), Ulivelli, Monica (AUTHOR)
Source: Neurological Sciences. Dec2024, Vol. 45 Issue 12, p5731-5737. 7p.
Subjects: Alzheimer's disease, Age groups, Degeneration (Pathology), Death rate, Older patients
Abstract: Objective: To evaluate mortality for Alzheimer's Disease (AD) in Italy over more than three decades (1980–2015) and discuss the possible role of general and specific contributing factors. Methods: Mortality data were extracted by the Italian National Institute of Statistics: crude mortality rates were computed for sex and age, considering the whole country and its five main geographical sub-areas. Rates were standardized in two ways: directly (annual mortality rates AMRs) and indirectly (standardized mortality rates, SMRs). SMRs were then used to evaluate geographical differences; to study mortality trend, AMRs and joinpoint linear regression analysis were used. Results: Considering the entire period and the whole country, mortality rates were similar for females and males and for geographical regions, with the exception of the older age groups where mortality for AD in females slightly prevailed. In these older patients, a steep increase of mortality was seen starting from the current century. The increase in male mortality mirrored the national trend in North-West and Central Italy, but not in North-East, South, and the Islands, where it did not surge until the mid to late 1990s. Conclusions: the general increase of mortality is in line with international data and it reflects the increasing prevalence of the disease, likely due to increasing longevity, and to improvements in diagnostic accuracy. In addition, the accuracy of death certificate compilation could account for both geographical and temporal differences. Currently available drugs for AD do not seem to have an impact on mortality rates. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 180829976
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Mortality of alzheimer's disease in Italy from 1980 to 2015.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Bezzini%2C+Daiana%22">Bezzini, Daiana</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Smeralda%2C+Carmelo+L%2E%22">Smeralda, Carmelo L.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pasqualetti%2C+Patrizio%22">Pasqualetti, Patrizio</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cappa%2C+Stefano+F%2E%22">Cappa, Stefano F.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kundisova%2C+Lucia%22">Kundisova, Lucia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rossi%2C+Simone%22">Rossi, Simone</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ulivelli%2C+Monica%22">Ulivelli, Monica</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. Dec2024, Vol. 45 Issue 12, p5731-5737. 7p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Alzheimer's+disease%22">Alzheimer's disease</searchLink><br /><searchLink fieldCode="DE" term="%22Age+groups%22">Age groups</searchLink><br /><searchLink fieldCode="DE" term="%22Degeneration+%28Pathology%29%22">Degeneration (Pathology)</searchLink><br /><searchLink fieldCode="DE" term="%22Death+rate%22">Death rate</searchLink><br /><searchLink fieldCode="DE" term="%22Older+patients%22">Older patients</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: To evaluate mortality for Alzheimer's Disease (AD) in Italy over more than three decades (1980–2015) and discuss the possible role of general and specific contributing factors. Methods: Mortality data were extracted by the Italian National Institute of Statistics: crude mortality rates were computed for sex and age, considering the whole country and its five main geographical sub-areas. Rates were standardized in two ways: directly (annual mortality rates AMRs) and indirectly (standardized mortality rates, SMRs). SMRs were then used to evaluate geographical differences; to study mortality trend, AMRs and joinpoint linear regression analysis were used. Results: Considering the entire period and the whole country, mortality rates were similar for females and males and for geographical regions, with the exception of the older age groups where mortality for AD in females slightly prevailed. In these older patients, a steep increase of mortality was seen starting from the current century. The increase in male mortality mirrored the national trend in North-West and Central Italy, but not in North-East, South, and the Islands, where it did not surge until the mid to late 1990s. Conclusions: the general increase of mortality is in line with international data and it reflects the increasing prevalence of the disease, likely due to increasing longevity, and to improvements in diagnostic accuracy. In addition, the accuracy of death certificate compilation could account for both geographical and temporal differences. Currently available drugs for AD do not seem to have an impact on mortality rates. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=180829976
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10072-024-07791-3
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 5731
    Subjects:
      – SubjectFull: Alzheimer's disease
        Type: general
      – SubjectFull: Age groups
        Type: general
      – SubjectFull: Degeneration (Pathology)
        Type: general
      – SubjectFull: Death rate
        Type: general
      – SubjectFull: Older patients
        Type: general
    Titles:
      – TitleFull: Mortality of alzheimer's disease in Italy from 1980 to 2015.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Bezzini, Daiana
      – PersonEntity:
          Name:
            NameFull: Smeralda, Carmelo L.
      – PersonEntity:
          Name:
            NameFull: Pasqualetti, Patrizio
      – PersonEntity:
          Name:
            NameFull: Cappa, Stefano F.
      – PersonEntity:
          Name:
            NameFull: Kundisova, Lucia
      – PersonEntity:
          Name:
            NameFull: Rossi, Simone
      – PersonEntity:
          Name:
            NameFull: Ulivelli, Monica
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 12
              Text: Dec2024
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-print
              Value: 15901874
          Numbering:
            – Type: volume
              Value: 45
            – Type: issue
              Value: 12
          Titles:
            – TitleFull: Neurological Sciences
              Type: main
ResultId 1