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A retrospective cohort study of prescription drug use among youth with intellectual/developmental disabilities in British Columbia.

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Title: A retrospective cohort study of prescription drug use among youth with intellectual/developmental disabilities in British Columbia.
Authors: Marquis, S., Marquis, N. E., Lunsky, Y., McGrail, K. M., Baumbusch, J.
Source: Journal of Intellectual Disability Research. Oct2024, Vol. 68 Issue 10, p1156-1166. 11p.
Subjects: Benzodiazepines, Thyroxine, Research funding, Retrospective studies, Amoxicillin, Antipsychotic agents, Tranquilizing drugs, Descriptive statistics, Intellectual disabilities, Developmental disabilities, Longitudinal method, Odds ratio, Antidepressants, Ganglionic stimulating agents, Medical records, Acquisition of data, Drugs, Albuterol, Comparative studies, Psychiatric drugs, Sympatholytic agents
Geographic Terms: British Columbia
Abstract: Background: People with intellectual/developmental disabilities (IDD) are known to have high rates of prescription drug use, particularly for psychotropic medications. This is of concern due to the many side effects associated with these medications and because of the risks of polypharmacy. In this paper we compare the most commonly dispensed drugs and all psychotropic medications for youth with IDD compared with youth without IDD. Methods: Using population‐level administrative health data over a 10‐year period, this study examined medications dispensed to youth with an IDD aged 15–24 years compared with youth without an IDD. The most common medications dispensed and the number of youth they were dispensed to were determined. As well a wide variety of psychotropic medications were examined. Results: There were a total of 20 591 youth with IDD and 1 293 791 youth without IDD identified. Youth with IDD had higher odds of being dispensed pain medications, amoxicillin, salbutamol, levothyroxine and all the psychotropic medications (antidepressants, antipsychotics, anxiolytics, anti‐adrenergic agents, mood stabilisers and stimulants). For youth with IDD, 6558 (31.85%) were dispensed two or more different psychotropic medications within a year, compared with 75 963 (5.87%) of youth without IDD. Discussion: Compared to youth without IDD, youth with IDD had significantly higher odds of being dispensed most of the prescription medications studied, including all of the psychotropic medications. They were also twice as likely to be dispensed two or more medications from different classes of psychotropic drugs within the same year. These findings have important implications for the health of people with IDD and for their health care providers. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Intellectual Disability Research is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: A retrospective cohort study of prescription drug use among youth with intellectual/developmental disabilities in British Columbia.
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  Data: <searchLink fieldCode="AR" term="%22Marquis%2C+S%2E%22">Marquis, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Marquis%2C+N%2E+E%2E%22">Marquis, N. E.</searchLink><br /><searchLink fieldCode="AR" term="%22Lunsky%2C+Y%2E%22">Lunsky, Y.</searchLink><br /><searchLink fieldCode="AR" term="%22McGrail%2C+K%2E+M%2E%22">McGrail, K. M.</searchLink><br /><searchLink fieldCode="AR" term="%22Baumbusch%2C+J%2E%22">Baumbusch, J.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Intellectual+Disability+Research%22">Journal of Intellectual Disability Research</searchLink>. Oct2024, Vol. 68 Issue 10, p1156-1166. 11p.
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  Data: <searchLink fieldCode="DE" term="%22Benzodiazepines%22">Benzodiazepines</searchLink><br /><searchLink fieldCode="DE" term="%22Thyroxine%22">Thyroxine</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Retrospective+studies%22">Retrospective studies</searchLink><br /><searchLink fieldCode="DE" term="%22Amoxicillin%22">Amoxicillin</searchLink><br /><searchLink fieldCode="DE" term="%22Antipsychotic+agents%22">Antipsychotic agents</searchLink><br /><searchLink fieldCode="DE" term="%22Tranquilizing+drugs%22">Tranquilizing drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Intellectual+disabilities%22">Intellectual disabilities</searchLink><br /><searchLink fieldCode="DE" term="%22Developmental+disabilities%22">Developmental disabilities</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22Odds+ratio%22">Odds ratio</searchLink><br /><searchLink fieldCode="DE" term="%22Antidepressants%22">Antidepressants</searchLink><br /><searchLink fieldCode="DE" term="%22Ganglionic+stimulating+agents%22">Ganglionic stimulating agents</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+records%22">Medical records</searchLink><br /><searchLink fieldCode="DE" term="%22Acquisition+of+data%22">Acquisition of data</searchLink><br /><searchLink fieldCode="DE" term="%22Drugs%22">Drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Albuterol%22">Albuterol</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Psychiatric+drugs%22">Psychiatric drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Sympatholytic+agents%22">Sympatholytic agents</searchLink>
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  Label: Geographic Terms
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  Data: <searchLink fieldCode="DE" term="%22British+Columbia%22">British Columbia</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: People with intellectual/developmental disabilities (IDD) are known to have high rates of prescription drug use, particularly for psychotropic medications. This is of concern due to the many side effects associated with these medications and because of the risks of polypharmacy. In this paper we compare the most commonly dispensed drugs and all psychotropic medications for youth with IDD compared with youth without IDD. Methods: Using population‐level administrative health data over a 10‐year period, this study examined medications dispensed to youth with an IDD aged 15–24 years compared with youth without an IDD. The most common medications dispensed and the number of youth they were dispensed to were determined. As well a wide variety of psychotropic medications were examined. Results: There were a total of 20 591 youth with IDD and 1 293 791 youth without IDD identified. Youth with IDD had higher odds of being dispensed pain medications, amoxicillin, salbutamol, levothyroxine and all the psychotropic medications (antidepressants, antipsychotics, anxiolytics, anti‐adrenergic agents, mood stabilisers and stimulants). For youth with IDD, 6558 (31.85%) were dispensed two or more different psychotropic medications within a year, compared with 75 963 (5.87%) of youth without IDD. Discussion: Compared to youth without IDD, youth with IDD had significantly higher odds of being dispensed most of the prescription medications studied, including all of the psychotropic medications. They were also twice as likely to be dispensed two or more medications from different classes of psychotropic drugs within the same year. These findings have important implications for the health of people with IDD and for their health care providers. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Journal of Intellectual Disability Research is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=180987636
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/jir.13147
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 1156
    Subjects:
      – SubjectFull: Benzodiazepines
        Type: general
      – SubjectFull: Thyroxine
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Retrospective studies
        Type: general
      – SubjectFull: Amoxicillin
        Type: general
      – SubjectFull: Antipsychotic agents
        Type: general
      – SubjectFull: Tranquilizing drugs
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Intellectual disabilities
        Type: general
      – SubjectFull: Developmental disabilities
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Odds ratio
        Type: general
      – SubjectFull: Antidepressants
        Type: general
      – SubjectFull: Ganglionic stimulating agents
        Type: general
      – SubjectFull: Medical records
        Type: general
      – SubjectFull: Acquisition of data
        Type: general
      – SubjectFull: Drugs
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      – SubjectFull: Albuterol
        Type: general
      – SubjectFull: Comparative studies
        Type: general
      – SubjectFull: Psychiatric drugs
        Type: general
      – SubjectFull: Sympatholytic agents
        Type: general
      – SubjectFull: British Columbia
        Type: general
    Titles:
      – TitleFull: A retrospective cohort study of prescription drug use among youth with intellectual/developmental disabilities in British Columbia.
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              M: 10
              Text: Oct2024
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              Y: 2024
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