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Blood Parameters in Children and Adolescents With Underweight and Atypical Anorexia Nervosa.

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Title: Blood Parameters in Children and Adolescents With Underweight and Atypical Anorexia Nervosa.
Authors: Flamarique, I., Pineda, M., Tasa‐Vinyals, E., Borràs, R., Susana, Andrés‐Perpiñá, Moreno, E., Martínez, E., Hilker, I., Plana, M. T., Mora, M., Castro‐Fornieles, J.
Source: International Journal of Eating Disorders. Jan2025, Vol. 58 Issue 1, p171-180. 10p.
Subjects: Anorexia nervosa complications, Risk assessment, Leanness, Body mass index, Blood collection, Biochemistry, Retrospective studies, Blood protein disorders, Pancytopenia, Estradiol, Medical records, Acquisition of data, Cholesterol, Alanine aminotransferase, Luteinizing hormone, Follicle-stimulating hormone, Endocrine diseases, Blood diseases, Somatomedin, Biomarkers, Serum albumin, Neutropenia, Disease risk factors, Adolescence, Children
Abstract: Objective: This study aimed to identify biochemical, hematological, and endocrinological abnormalities in a sample of children and adolescents with underweight AN and atypical AN and to compare these results between the two groups. Method: Based on the 5th BMI‐percentile admission, adolescents with underweight AN (n = 520) and atypical AN (n = 255) were included and medical records were reviewed. Results: Low prealbumin (35%) and neutropenia (39%), and several abnormalities in endocrinological parameters (50%) were the most common alterations found in the whole sample. Compared to the atypical AN group, the underweight AN group had significantly higher frequencies of elevated cholesterol (OR = 2.50; p < 0.001) and alanine aminotransferase (OR = 0.22; p = 0.005) and of reduced insulin‐like growth (IGF) factor‐1 (OR = 0.29; p < 0.001), T3 (OR = 0.46; p < 0.001), luteinizing hormone (OR = 0.24; p < 0.001), follicle stimulating hormone (OR = 0.58; p = 0.004), and 17b‐estradiol (OR = 0.39; p < 0.001). However, other blood parameters showed similar alterations in both groups. Discussion: Both groups showed abnormalities in the same blood parameters, but some abnormal parameters were more common in the underweight AN group. These results suggest that atypical AN and underweight AN could present similar risks of certain medical complications. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Blood Parameters in Children and Adolescents With Underweight and Atypical Anorexia Nervosa.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22International+Journal+of+Eating+Disorders%22&quot;&gt;International Journal of Eating Disorders&lt;/searchLink&gt;. Jan2025, Vol. 58 Issue 1, p171-180. 10p.
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  Data: Objective: This study aimed to identify biochemical, hematological, and endocrinological abnormalities in a sample of children and adolescents with underweight AN and atypical AN and to compare these results between the two groups. Method: Based on the 5th BMI‐percentile admission, adolescents with underweight AN (n = 520) and atypical AN (n = 255) were included and medical records were reviewed. Results: Low prealbumin (35%) and neutropenia (39%), and several abnormalities in endocrinological parameters (50%) were the most common alterations found in the whole sample. Compared to the atypical AN group, the underweight AN group had significantly higher frequencies of elevated cholesterol (OR = 2.50; p &lt; 0.001) and alanine aminotransferase (OR = 0.22; p = 0.005) and of reduced insulin‐like growth (IGF) factor‐1 (OR = 0.29; p &lt; 0.001), T3 (OR = 0.46; p &lt; 0.001), luteinizing hormone (OR = 0.24; p &lt; 0.001), follicle stimulating hormone (OR = 0.58; p = 0.004), and 17b‐estradiol (OR = 0.39; p &lt; 0.001). However, other blood parameters showed similar alterations in both groups. Discussion: Both groups showed abnormalities in the same blood parameters, but some abnormal parameters were more common in the underweight AN group. These results suggest that atypical AN and underweight AN could present similar risks of certain medical complications. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=183925843
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        Value: 10.1002/eat.24272
    Languages:
      – Code: eng
        Text: English
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        PageCount: 10
        StartPage: 171
    Subjects:
      – SubjectFull: Anorexia nervosa complications
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Leanness
        Type: general
      – SubjectFull: Body mass index
        Type: general
      – SubjectFull: Blood collection
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      – SubjectFull: Biochemistry
        Type: general
      – SubjectFull: Retrospective studies
        Type: general
      – SubjectFull: Blood protein disorders
        Type: general
      – SubjectFull: Pancytopenia
        Type: general
      – SubjectFull: Estradiol
        Type: general
      – SubjectFull: Medical records
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      – SubjectFull: Acquisition of data
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      – SubjectFull: Cholesterol
        Type: general
      – SubjectFull: Alanine aminotransferase
        Type: general
      – SubjectFull: Luteinizing hormone
        Type: general
      – SubjectFull: Follicle-stimulating hormone
        Type: general
      – SubjectFull: Endocrine diseases
        Type: general
      – SubjectFull: Blood diseases
        Type: general
      – SubjectFull: Somatomedin
        Type: general
      – SubjectFull: Biomarkers
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      – SubjectFull: Serum albumin
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        Type: general
      – SubjectFull: Disease risk factors
        Type: general
      – SubjectFull: Adolescence
        Type: general
      – SubjectFull: Children
        Type: general
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      – TitleFull: Blood Parameters in Children and Adolescents With Underweight and Atypical Anorexia Nervosa.
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              Text: Jan2025
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