Assessment and Correlates of Different Phenotypical Characteristics of Psychological Flexibility in Adapting to Chronic Pain: A Feasibility Study.

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Title: Assessment and Correlates of Different Phenotypical Characteristics of Psychological Flexibility in Adapting to Chronic Pain: A Feasibility Study.
Authors: Legierse, Ivo P., van Middendorp, Henriët, Borgonjen, Maike, Bronkhorst, Ewald M., Pisters, Martijn F., Vissers, Kris C. P., Steegers, Monique A. H.
Source: Pain Practice. Jun2025, Vol. 25 Issue 5, p1-17. 17p.
Subjects: Chronic pain & psychology, Pain measurement, Cross-sectional method, Pearson correlation (Statistics), Academic medical centers, Data analysis, Research funding, Pilot projects, Psychological adaptation, Descriptive statistics, Anxiety, Statistics, Pain management, Data analysis software, Phenotypes, Mental depression
Geographic Terms: Netherlands
Abstract: Objectives: This study examined the feasibility of a research protocol for assessing psychological flexibility in patients with chronic pain to gain insight into the uniqueness of different phenotypes of psychological flexibility and to tentatively test whether psychological flexibility is associated with effective adaptation to chronic pain. Methods: In a cross‐sectional study, in twenty patients with chronic pain, different phenotypes of psychological flexibility and a variety of positive and negative health indicators were assessed. Correlations were explored to determine the unicity of the different phenotypes of psychological flexibility and to test their associations with chronic pain. Results: All phenotypes of psychological flexibility could be assessed reliably in this patient group. Preliminary findings suggest that all phenotypes assess unique flexibility aspects (79% of the intercorrelations were less than moderate; > −0.30, < 0.30). Higher levels of different psychological flexibility phenotypes were generally associated with higher positive health indicators and lower negative health indicators (70% of the moderate correlations; ≤ −0.30 or ≥ 0.30 were in the expected direction). Conclusions: Results confirm that the protocol is feasible for large‐scale research in patients with chronic pain and that it is useful to further investigate the different phenotypes of psychological flexibility in relation to optimal adaptation to chronic pain in a longitudinal study. Practice Implications: Psychological flexibility is a potentially important future target in the treatment (e.g., biofeedback, cognitive behavioral therapy, mindfulness) of patients with chronic pain. [ABSTRACT FROM AUTHOR]
Copyright of Pain Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Pain+Practice%22&quot;&gt;Pain Practice&lt;/searchLink&gt;. Jun2025, Vol. 25 Issue 5, p1-17. 17p.
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  Data: Objectives: This study examined the feasibility of a research protocol for assessing psychological flexibility in patients with chronic pain to gain insight into the uniqueness of different phenotypes of psychological flexibility and to tentatively test whether psychological flexibility is associated with effective adaptation to chronic pain. Methods: In a cross‐sectional study, in twenty patients with chronic pain, different phenotypes of psychological flexibility and a variety of positive and negative health indicators were assessed. Correlations were explored to determine the unicity of the different phenotypes of psychological flexibility and to test their associations with chronic pain. Results: All phenotypes of psychological flexibility could be assessed reliably in this patient group. Preliminary findings suggest that all phenotypes assess unique flexibility aspects (79% of the intercorrelations were less than moderate; &gt; −0.30, &lt; 0.30). Higher levels of different psychological flexibility phenotypes were generally associated with higher positive health indicators and lower negative health indicators (70% of the moderate correlations; ≤ −0.30 or ≥ 0.30 were in the expected direction). Conclusions: Results confirm that the protocol is feasible for large‐scale research in patients with chronic pain and that it is useful to further investigate the different phenotypes of psychological flexibility in relation to optimal adaptation to chronic pain in a longitudinal study. Practice Implications: Psychological flexibility is a potentially important future target in the treatment (e.g., biofeedback, cognitive behavioral therapy, mindfulness) of patients with chronic pain. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Pain Practice is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1111/papr.70047
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      – Code: eng
        Text: English
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        PageCount: 17
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    Subjects:
      – SubjectFull: Chronic pain & psychology
        Type: general
      – SubjectFull: Pain measurement
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Pearson correlation (Statistics)
        Type: general
      – SubjectFull: Academic medical centers
        Type: general
      – SubjectFull: Data analysis
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Pilot projects
        Type: general
      – SubjectFull: Psychological adaptation
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Anxiety
        Type: general
      – SubjectFull: Statistics
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      – SubjectFull: Pain management
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      – SubjectFull: Data analysis software
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      – SubjectFull: Phenotypes
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      – SubjectFull: Mental depression
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      – SubjectFull: Netherlands
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      – TitleFull: Assessment and Correlates of Different Phenotypical Characteristics of Psychological Flexibility in Adapting to Chronic Pain: A Feasibility Study.
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              Text: Jun2025
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              Y: 2025
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