Effects of WeChat-based EPIC training on health-related quality of life, attribution and life attitude in women newly diagnosed with breast cancer: a clinical randomized controlled trial.

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Title: Effects of WeChat-based EPIC training on health-related quality of life, attribution and life attitude in women newly diagnosed with breast cancer: a clinical randomized controlled trial.
Authors: Zhou, Kaina (AUTHOR), Wang, Xiao (AUTHOR), Wang, Yan (AUTHOR), Liu, Ailan (AUTHOR)
Source: Quality of Life Research. Jul2025, Vol. 34 Issue 7, p1979-1993. 15p.
Subjects: Quality of life, Breast cancer, Clinical health psychology, WeChat (Web resource), Attribution (Social psychology), Psychological resilience, Clinical trials, Females
Abstract: Purpose: When confronted with healthy functional impairments, the attribution of disease-induced distress plays a key role in the prognosis of health outcomes. This study examined the effects of an attribution-related intervention, namely WeChat-based EPIC (enter, practice, intensify, consolidate) training, on health-related quality of life (HRQoL), attribution, and life attitude in women newly diagnosed with breast cancer. Methods: Eligible patients were recruited using convenience sampling and randomly assigned to the intervention or control group via stratified block randomization. The former received WeChat-based EPIC training plus routine nursing care for 6 months. The latter received only routine nursing care. HRQoL (primary indicator), attribution and life attitude (secondary indicators) were measured using the Functional Assessment of Cancer Therapy-Breast version 4.0 (FACT-Bv4.0), Attributional Style Questionnaire (ASQ) and Life Attitude Self-rating Questionnaire for Breast Cancer (LASQ-BC), respectively. A linear mixed model was used to examine the score fluctuations at the 1-, 3-, and 6-month intervals relative to the baseline. Results: After 6 months, the intervention group (n = 84) showed statistically significant higher total scores in the FACT-Bv4.0 [mean difference: − 15.01; 95% confidence interval: − 17.96, − 12.07; p < 0.001], ASQ [− 4.16 (− 4.45, − 3.86); p < 0.001], and LASQ-BC [− 6.77 (− 8.27, − 5.27); p < 0.001] than that of the control group (n = 82). The total scores of the three indicators also showed significant group, time, and group-by-time interaction effects (p < 0.001). Conclusion: The WeChat-based EPIC training was an effective intervention for improving HRQoL and psychological health in women newly diagnosed with breast cancer. Trial registration: Chinese Clinical Trial Registry www.chictr.org.cn, prospectively registered on 11 April 2020, ChiCTR2000031827. [ABSTRACT FROM AUTHOR]
Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Effects of WeChat-based EPIC training on health-related quality of life, attribution and life attitude in women newly diagnosed with breast cancer: a clinical randomized controlled trial.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Quality+of+Life+Research%22&quot;&gt;Quality of Life Research&lt;/searchLink&gt;. Jul2025, Vol. 34 Issue 7, p1979-1993. 15p.
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  Label: Abstract
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  Data: Purpose: When confronted with healthy functional impairments, the attribution of disease-induced distress plays a key role in the prognosis of health outcomes. This study examined the effects of an attribution-related intervention, namely WeChat-based EPIC (enter, practice, intensify, consolidate) training, on health-related quality of life (HRQoL), attribution, and life attitude in women newly diagnosed with breast cancer. Methods: Eligible patients were recruited using convenience sampling and randomly assigned to the intervention or control group via stratified block randomization. The former received WeChat-based EPIC training plus routine nursing care for 6 months. The latter received only routine nursing care. HRQoL (primary indicator), attribution and life attitude (secondary indicators) were measured using the Functional Assessment of Cancer Therapy-Breast version 4.0 (FACT-Bv4.0), Attributional Style Questionnaire (ASQ) and Life Attitude Self-rating Questionnaire for Breast Cancer (LASQ-BC), respectively. A linear mixed model was used to examine the score fluctuations at the 1-, 3-, and 6-month intervals relative to the baseline. Results: After 6 months, the intervention group (n = 84) showed statistically significant higher total scores in the FACT-Bv4.0 [mean difference: − 15.01; 95% confidence interval: − 17.96, − 12.07; p &lt; 0.001], ASQ [− 4.16 (− 4.45, − 3.86); p &lt; 0.001], and LASQ-BC [− 6.77 (− 8.27, − 5.27); p &lt; 0.001] than that of the control group (n = 82). The total scores of the three indicators also showed significant group, time, and group-by-time interaction effects (p &lt; 0.001). Conclusion: The WeChat-based EPIC training was an effective intervention for improving HRQoL and psychological health in women newly diagnosed with breast cancer. Trial registration: Chinese Clinical Trial Registry www.chictr.org.cn, prospectively registered on 11 April 2020, ChiCTR2000031827. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1007/s11136-025-03959-2
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        Text: English
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        StartPage: 1979
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      – SubjectFull: Quality of life
        Type: general
      – SubjectFull: Breast cancer
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      – SubjectFull: Clinical health psychology
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      – SubjectFull: WeChat (Web resource)
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      – SubjectFull: Females
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      – TitleFull: Effects of WeChat-based EPIC training on health-related quality of life, attribution and life attitude in women newly diagnosed with breast cancer: a clinical randomized controlled trial.
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              Text: Jul2025
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