The importance of incorporation of real-world evidence into the guidelines on the pharmacological treatment of schizophrenia.
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| Title: | The importance of incorporation of real-world evidence into the guidelines on the pharmacological treatment of schizophrenia. |
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| Authors: | Bitter, Istvan (AUTHOR), Katona, Lajos (AUTHOR), Falkai, Peter (AUTHOR), Czobor, Pal (AUTHOR) |
| Source: | European Archives of Psychiatry & Clinical Neuroscience. Aug2025, Vol. 275 Issue 5, p1521-1523. 3p. |
| Subjects: | Schizophrenia, Drug therapy, Medical care research, Comparative studies, Empirical research, Medical protocols, Clinical trials |
| Abstract: | The quantity and quality of real-world data and real-world evidence in schizophrenia research are at a high level. However, these results are not included in the grading systems used to develop treatment guidelines for schizophrenia. A meta-analysis and a network meta-analysis have independently provided evidence that the results of randomized clinical trials in schizophrenia adequately translate to real-world settings. The authors propose the incorporation of a synthesis of evidence derived from analyses of randomized controlled trials and real-world data as a novel and highest level of evidence in grading instruments used to develop treatment guidelines for schizophrenia. [ABSTRACT FROM AUTHOR] |
| Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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