Neurobiology of Thirst and Hunger Drives.

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Title: Neurobiology of Thirst and Hunger Drives.
Authors: Encarnacion-Rivera, Lucas (AUTHOR), Deisseroth, Karl (AUTHOR), Luo, Liqun (AUTHOR)
Source: Annual Review of Neuroscience. Jul2025, Vol. 48 Issue 1, p381-403. 24p.
Subjects: Neural circuitry, Circuit elements, Hunger, Thirst, Starvation
Abstract: Thirst and hunger drives are fundamental survival mechanisms that transform physiological need into motivated behavior. In the brain, discrete types of circumventricular and hypothalamic neurons serve as neural circuit elements underlying thirst and hunger drives. These neurons receive signals of dehydration and starvation arising from outside the brain and communicate these homeostatic needs to downstream neural circuit elements. Recent advances in neural circuit activity recording and control in behaving mammals have elucidated how direct and indirect targets of these cells encode goal-relevant, affective, autonomic, and behavioral components of the drives, resulting in a finely tuned, robust, and flexible set of survival-appropriate behaviors. [ABSTRACT FROM AUTHOR]
Copyright of Annual Review of Neuroscience is the property of Annual Reviews Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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DbLabel: Psychology and Behavioral Sciences Collection
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Neurobiology of Thirst and Hunger Drives.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Encarnacion-Rivera%2C+Lucas%22">Encarnacion-Rivera, Lucas</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Deisseroth%2C+Karl%22">Deisseroth, Karl</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Luo%2C+Liqun%22">Luo, Liqun</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Annual+Review+of+Neuroscience%22">Annual Review of Neuroscience</searchLink>. Jul2025, Vol. 48 Issue 1, p381-403. 24p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Neural+circuitry%22">Neural circuitry</searchLink><br /><searchLink fieldCode="DE" term="%22Circuit+elements%22">Circuit elements</searchLink><br /><searchLink fieldCode="DE" term="%22Hunger%22">Hunger</searchLink><br /><searchLink fieldCode="DE" term="%22Thirst%22">Thirst</searchLink><br /><searchLink fieldCode="DE" term="%22Starvation%22">Starvation</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Thirst and hunger drives are fundamental survival mechanisms that transform physiological need into motivated behavior. In the brain, discrete types of circumventricular and hypothalamic neurons serve as neural circuit elements underlying thirst and hunger drives. These neurons receive signals of dehydration and starvation arising from outside the brain and communicate these homeostatic needs to downstream neural circuit elements. Recent advances in neural circuit activity recording and control in behaving mammals have elucidated how direct and indirect targets of these cells encode goal-relevant, affective, autonomic, and behavioral components of the drives, resulting in a finely tuned, robust, and flexible set of survival-appropriate behaviors. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Annual Review of Neuroscience is the property of Annual Reviews Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1146/annurev-neuro-112723-032328
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 24
        StartPage: 381
    Subjects:
      – SubjectFull: Neural circuitry
        Type: general
      – SubjectFull: Circuit elements
        Type: general
      – SubjectFull: Hunger
        Type: general
      – SubjectFull: Thirst
        Type: general
      – SubjectFull: Starvation
        Type: general
    Titles:
      – TitleFull: Neurobiology of Thirst and Hunger Drives.
        Type: main
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          Name:
            NameFull: Encarnacion-Rivera, Lucas
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          Name:
            NameFull: Deisseroth, Karl
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          Name:
            NameFull: Luo, Liqun
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          Dates:
            – D: 01
              M: 07
              Text: Jul2025
              Type: published
              Y: 2025
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              Value: 48
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            – TitleFull: Annual Review of Neuroscience
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