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Prevalence of anxiety, depression, and suicidality in adolescents with parental severe mental illness: a controlled study in China.

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Title: Prevalence of anxiety, depression, and suicidality in adolescents with parental severe mental illness: a controlled study in China.
Authors: Zhang, Shengmin, Zhou, Tianhang, Zhou, Yongtao, Chen, Weiran, Meng, Xinyu, Tian, Shaoli, Xiang, Hu, Zhu, Lingyan, Wen, Liping, Chen, Sijing, Chen, Wencai, Ge, Ling, Liang, Guangming, Ding, Yongzhuo, Deng, Hua, Pan, Yang, Zhang, Changchun, Ji, Shujiao, Hong, Xu, Chang, Zhengjiao
Source: Journal of Mental Health. Aug2025, Vol. 34 Issue 4, p420-430. 11p.
Subjects: Self-evaluation, Cross-sectional method, Suicidal ideation, Adolescent health, Research funding, Psychological distress, T-test (Statistics), Children of parents with disabilities, Mental illness, Fisher exact test, Logistic regression analysis, Anxiety, Family relations, Mann Whitney U Test, Chi-squared test, Multivariate analysis, Descriptive statistics, Communication, Research, Statistics, Psychology of parents, Comparative studies, Factor analysis, Data analysis software, Psychosocial factors, Mental depression, Adolescence
Geographic Terms: China
Abstract: Background: Children of parents with mental illness (COPMI) have not received sufficient support in China despite their genetic and environmental risk of adverse mental health outcomes. Aims: This study was conducted for the first time in China to assess mental distress in adolescent COPMI compared with the population-based control (PBC) group of parents without mental disorders. Methods: A total of 1,114 participants including 558 COPMI and 556 PBC, aged 12–17, were recruited from the communities and assessed by self-report scales about anxiety, depression, and suicidality. Regression and mediation analyses were used to identify risk factors for mental distress. Results: The estimated prevalence of anxiety and depression in the COPMI group was significantly higher than in the PBC group (anxiety: 3.9% vs. 1.6%, depression: 5.9% vs. 3.4%). A history of parental mental illness was associated with the lack of family communication, which in turn had a significant (BootCI = (0.020 − 0.062)) indirect effect on the increased anxiety and depression levels of the adolescent offspring. Conclusions: Our findings emphasized the necessity to early identify mental distress in COPMI and provide timely and targeted intervention to improve family communication and mental health well-being for these high-risk adolescents. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Mental Health is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Label: Title
  Group: Ti
  Data: Prevalence of anxiety, depression, and suicidality in adolescents with parental severe mental illness: a controlled study in China.
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  Data: <searchLink fieldCode="AR" term="%22Zhang%2C+Shengmin%22">Zhang, Shengmin</searchLink><br /><searchLink fieldCode="AR" term="%22Zhou%2C+Tianhang%22">Zhou, Tianhang</searchLink><br /><searchLink fieldCode="AR" term="%22Zhou%2C+Yongtao%22">Zhou, Yongtao</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Weiran%22">Chen, Weiran</searchLink><br /><searchLink fieldCode="AR" term="%22Meng%2C+Xinyu%22">Meng, Xinyu</searchLink><br /><searchLink fieldCode="AR" term="%22Tian%2C+Shaoli%22">Tian, Shaoli</searchLink><br /><searchLink fieldCode="AR" term="%22Xiang%2C+Hu%22">Xiang, Hu</searchLink><br /><searchLink fieldCode="AR" term="%22Zhu%2C+Lingyan%22">Zhu, Lingyan</searchLink><br /><searchLink fieldCode="AR" term="%22Wen%2C+Liping%22">Wen, Liping</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Sijing%22">Chen, Sijing</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Wencai%22">Chen, Wencai</searchLink><br /><searchLink fieldCode="AR" term="%22Ge%2C+Ling%22">Ge, Ling</searchLink><br /><searchLink fieldCode="AR" term="%22Liang%2C+Guangming%22">Liang, Guangming</searchLink><br /><searchLink fieldCode="AR" term="%22Ding%2C+Yongzhuo%22">Ding, Yongzhuo</searchLink><br /><searchLink fieldCode="AR" term="%22Deng%2C+Hua%22">Deng, Hua</searchLink><br /><searchLink fieldCode="AR" term="%22Pan%2C+Yang%22">Pan, Yang</searchLink><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Changchun%22">Zhang, Changchun</searchLink><br /><searchLink fieldCode="AR" term="%22Ji%2C+Shujiao%22">Ji, Shujiao</searchLink><br /><searchLink fieldCode="AR" term="%22Hong%2C+Xu%22">Hong, Xu</searchLink><br /><searchLink fieldCode="AR" term="%22Chang%2C+Zhengjiao%22">Chang, Zhengjiao</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Mental+Health%22">Journal of Mental Health</searchLink>. Aug2025, Vol. 34 Issue 4, p420-430. 11p.
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  Data: <searchLink fieldCode="DE" term="%22Self-evaluation%22">Self-evaluation</searchLink><br /><searchLink fieldCode="DE" term="%22Cross-sectional+method%22">Cross-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22Suicidal+ideation%22">Suicidal ideation</searchLink><br /><searchLink fieldCode="DE" term="%22Adolescent+health%22">Adolescent health</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Psychological+distress%22">Psychological distress</searchLink><br /><searchLink fieldCode="DE" term="%22T-test+%28Statistics%29%22">T-test (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Children+of+parents+with+disabilities%22">Children of parents with disabilities</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+illness%22">Mental illness</searchLink><br /><searchLink fieldCode="DE" term="%22Fisher+exact+test%22">Fisher exact test</searchLink><br /><searchLink fieldCode="DE" term="%22Logistic+regression+analysis%22">Logistic regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety%22">Anxiety</searchLink><br /><searchLink fieldCode="DE" term="%22Family+relations%22">Family relations</searchLink><br /><searchLink fieldCode="DE" term="%22Mann+Whitney+U+Test%22">Mann Whitney U Test</searchLink><br /><searchLink fieldCode="DE" term="%22Chi-squared+test%22">Chi-squared test</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Communication%22">Communication</searchLink><br /><searchLink fieldCode="DE" term="%22Research%22">Research</searchLink><br /><searchLink fieldCode="DE" term="%22Statistics%22">Statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+parents%22">Psychology of parents</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Factor+analysis%22">Factor analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Psychosocial+factors%22">Psychosocial factors</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Adolescence%22">Adolescence</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22China%22">China</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Children of parents with mental illness (COPMI) have not received sufficient support in China despite their genetic and environmental risk of adverse mental health outcomes. Aims: This study was conducted for the first time in China to assess mental distress in adolescent COPMI compared with the population-based control (PBC) group of parents without mental disorders. Methods: A total of 1,114 participants including 558 COPMI and 556 PBC, aged 12–17, were recruited from the communities and assessed by self-report scales about anxiety, depression, and suicidality. Regression and mediation analyses were used to identify risk factors for mental distress. Results: The estimated prevalence of anxiety and depression in the COPMI group was significantly higher than in the PBC group (anxiety: 3.9% vs. 1.6%, depression: 5.9% vs. 3.4%). A history of parental mental illness was associated with the lack of family communication, which in turn had a significant (BootCI = (0.020 − 0.062)) indirect effect on the increased anxiety and depression levels of the adolescent offspring. Conclusions: Our findings emphasized the necessity to early identify mental distress in COPMI and provide timely and targeted intervention to improve family communication and mental health well-being for these high-risk adolescents. [ABSTRACT FROM AUTHOR]
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  Label:
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  Data: <i>Copyright of Journal of Mental Health is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/09638237.2025.2512309
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      – Code: eng
        Text: English
    PhysicalDescription:
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        PageCount: 11
        StartPage: 420
    Subjects:
      – SubjectFull: Self-evaluation
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Suicidal ideation
        Type: general
      – SubjectFull: Adolescent health
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      – SubjectFull: Research funding
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      – SubjectFull: Psychological distress
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      – SubjectFull: T-test (Statistics)
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      – SubjectFull: Children of parents with disabilities
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      – SubjectFull: Mental illness
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      – SubjectFull: Fisher exact test
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      – SubjectFull: Logistic regression analysis
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      – SubjectFull: Anxiety
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      – SubjectFull: Mann Whitney U Test
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      – SubjectFull: Chi-squared test
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      – SubjectFull: Communication
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      – SubjectFull: Adolescence
        Type: general
      – SubjectFull: China
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      – TitleFull: Prevalence of anxiety, depression, and suicidality in adolescents with parental severe mental illness: a controlled study in China.
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