Psychiatric antecedents in young patients with first episode psychosis: what relevance for clinical outcomes?
Saved in:
| Title: | Psychiatric antecedents in young patients with first episode psychosis: what relevance for clinical outcomes? |
|---|---|
| Authors: | Pelizza, Lorenzo (AUTHOR), Catalano, Fabio (AUTHOR), Leuci, Emanuela (AUTHOR), Quattrone, Emanuela (AUTHOR), Palmisano, Derna (AUTHOR), Pupo, Simona (AUTHOR), Paulillo, Giuseppina (AUTHOR), Pellegrini, Clara (AUTHOR), Pellegrini, Pietro (AUTHOR), Menchetti, Marco (AUTHOR) |
| Source: | European Archives of Psychiatry & Clinical Neuroscience. Dec2025, Vol. 275 Issue 8, p2535-2546. 12p. |
| Subjects: | Help-seeking behavior, Mental illness, Psychoses, Mental health services, Treatment effectiveness, Sociodemographic factors |
| Abstract: | Examining psychiatric antecedents and help-seeking behavior for people with First Episode Psychosis (FEP) could help understand determinants for timely care pathways, decrease the "Duration of Untreated Psychosis" (DUP), and consequently improve their prognosis. The aims of this study were: (1) to calculate the proportion of FEP participants with previous contact with mental healthcare services recruited within a specialized "Early Intervention in Psychosis" service, and (2) to longitudinally compare sociodemographic, clinical, and treatment parameters between FEP patients with and without psychiatric antecedents across a 2-year follow-up period. All participants (aged 12–35 years) were enrolled within the "Parma Early Psychosis" (Pr-EP) program. At baseline, they completed the Health of the Nation Outcome Scale (HoNOS). A mixed-design ANOVA and a Kaplan–Meier survival analysis were used. Of the 489 FEP participants, 204 (41.7%) patients had prior contact with mental health services. In 83% of cases, a care discontinuity was observed. Main psychiatric antecedents at entry were personality disorders (32.8%), anxious-depressive disorder (28.9%), conduct disorder (16.2%), and learning disorder (9.8%). FEP subjects with antecedents were more likely to receive a diagnosis of schizophrenia at baseline. Having previous contact with psychiatric services resulted to be a predictor of poorer clinical and functional outcome. It is very important to carefully monitor mental health suffering and related help-seeking-behavior in young patients typically manifested in their early 20s, especially in terms of psychosis prevention. Particular attention should also be given to service engagement as care continuity within adolescent-adult transition. [ABSTRACT FROM AUTHOR] |
| Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 189532973 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Psychiatric antecedents in young patients with first episode psychosis: what relevance for clinical outcomes? – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Pelizza%2C+Lorenzo%22">Pelizza, Lorenzo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Catalano%2C+Fabio%22">Catalano, Fabio</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Leuci%2C+Emanuela%22">Leuci, Emanuela</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Quattrone%2C+Emanuela%22">Quattrone, Emanuela</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Palmisano%2C+Derna%22">Palmisano, Derna</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pupo%2C+Simona%22">Pupo, Simona</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Paulillo%2C+Giuseppina%22">Paulillo, Giuseppina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pellegrini%2C+Clara%22">Pellegrini, Clara</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pellegrini%2C+Pietro%22">Pellegrini, Pietro</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Menchetti%2C+Marco%22">Menchetti, Marco</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Archives+of+Psychiatry+%26+Clinical+Neuroscience%22">European Archives of Psychiatry & Clinical Neuroscience</searchLink>. Dec2025, Vol. 275 Issue 8, p2535-2546. 12p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Help-seeking+behavior%22">Help-seeking behavior</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+illness%22">Mental illness</searchLink><br /><searchLink fieldCode="DE" term="%22Psychoses%22">Psychoses</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+health+services%22">Mental health services</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Sociodemographic+factors%22">Sociodemographic factors</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Examining psychiatric antecedents and help-seeking behavior for people with First Episode Psychosis (FEP) could help understand determinants for timely care pathways, decrease the "Duration of Untreated Psychosis" (DUP), and consequently improve their prognosis. The aims of this study were: (1) to calculate the proportion of FEP participants with previous contact with mental healthcare services recruited within a specialized "Early Intervention in Psychosis" service, and (2) to longitudinally compare sociodemographic, clinical, and treatment parameters between FEP patients with and without psychiatric antecedents across a 2-year follow-up period. All participants (aged 12–35 years) were enrolled within the "Parma Early Psychosis" (Pr-EP) program. At baseline, they completed the Health of the Nation Outcome Scale (HoNOS). A mixed-design ANOVA and a Kaplan–Meier survival analysis were used. Of the 489 FEP participants, 204 (41.7%) patients had prior contact with mental health services. In 83% of cases, a care discontinuity was observed. Main psychiatric antecedents at entry were personality disorders (32.8%), anxious-depressive disorder (28.9%), conduct disorder (16.2%), and learning disorder (9.8%). FEP subjects with antecedents were more likely to receive a diagnosis of schizophrenia at baseline. Having previous contact with psychiatric services resulted to be a predictor of poorer clinical and functional outcome. It is very important to carefully monitor mental health suffering and related help-seeking-behavior in young patients typically manifested in their early 20s, especially in terms of psychosis prevention. Particular attention should also be given to service engagement as care continuity within adolescent-adult transition. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=189532973 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00406-025-01981-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 2535 Subjects: – SubjectFull: Help-seeking behavior Type: general – SubjectFull: Mental illness Type: general – SubjectFull: Psychoses Type: general – SubjectFull: Mental health services Type: general – SubjectFull: Treatment effectiveness Type: general – SubjectFull: Sociodemographic factors Type: general Titles: – TitleFull: Psychiatric antecedents in young patients with first episode psychosis: what relevance for clinical outcomes? Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pelizza, Lorenzo – PersonEntity: Name: NameFull: Catalano, Fabio – PersonEntity: Name: NameFull: Leuci, Emanuela – PersonEntity: Name: NameFull: Quattrone, Emanuela – PersonEntity: Name: NameFull: Palmisano, Derna – PersonEntity: Name: NameFull: Pupo, Simona – PersonEntity: Name: NameFull: Paulillo, Giuseppina – PersonEntity: Name: NameFull: Pellegrini, Clara – PersonEntity: Name: NameFull: Pellegrini, Pietro – PersonEntity: Name: NameFull: Menchetti, Marco IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 09401334 Numbering: – Type: volume Value: 275 – Type: issue Value: 8 Titles: – TitleFull: European Archives of Psychiatry & Clinical Neuroscience Type: main |
| ResultId | 1 |
