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The interplay of HIV, female sexual dysfunction and quality of life among women in North-western Nigeria: a comparative study.

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Title: The interplay of HIV, female sexual dysfunction and quality of life among women in North-western Nigeria: a comparative study.
Authors: Damagum, Fatima M. (AUTHOR), Jalo, Rabiu I. (AUTHOR), Ahmed, Zainab D. (AUTHOR), Muhammad, Murtala A. (AUTHOR), Salihu, Hamisu M. (AUTHOR), Maiyaki, Baba M. (AUTHOR), William, Wester C. (AUTHOR), Aliyu, Muktar H. (AUTHOR)
Source: AIDS Care. Feb2026, Vol. 38 Issue 2, p388-395. 8p.
Subjects: Female reproductive organ diseases, Holistic medicine, Cross-sectional method, Academic medical centers, T-test (Statistics), Research funding, HIV-positive persons, Multiple regression analysis, Questionnaires, Orgasm, Sexual excitement, Psychology of women, Psychological well-being, Chi-squared test, Descriptive statistics, Highly active antiretroviral therapy, Sexual dysfunction, Quality of life, Comparative studies, Interpersonal relations, Resource-limited settings, Confidence intervals
Geographic Terms: Nigeria
Abstract: Background: Antiretroviral therapy has markedly increased life expectancy among people living with human immunodeficiency virus (HIV), yet the long-term impact of chronic HIV infection on women's quality of life (QoL) and sexual functioning remains poorly understood. Female sexual dysfunction (FSD) is common in women and may impair psychological well-being and social relationships. Understanding how HIV infection intersects with FSD and QoL could inform holistic care for women in resource-limited settings. Objective: To compare QoL and FSD between women living with HIV and HIV-negative women and to identify socio-demographic predictors of poor QoL. Methods: We conducted a hospital-based cross-sectional study in 2024 among 200 women on antiretroviral therapy and 200 age-matched HIV-negative women attending the general outpatient clinic at Aminu Kano Teaching Hospital, Kano, Nigeria. Participants were recruited through systematic sampling; research assistants provided study information and obtained written informed consent. Quality of life was assessed with the World Health Organization Quality of Life 26-item Brief questionnaire (WHOQOL-BREF). Female sexual function was screened with the 19-item Female Sexual Function Index (FSFI); a total score ≤26.55 denoted FSD. Data were analyzed using chi-square tests, independent t-tests and multivariable logistic regression. Results: The mean (±SD) age of participants was 37.1 ± 9.4 years. Overall QoL was significantly worse among women with HIV than HIV-negative women (53% vs 63% reporting good QoL, p = 0.043). Mean QoL scores were lower in the HIV-positive group for the psychological (61 ± 18 vs 54 ± 14; p < 0.001) and environmental domains (69 ± 20 vs 65 ± 16; p < 0.001), while physical and social domain scores were comparable. FSD was highly prevalent in both groups (96% in HIV-positive and 98% in HIV-negative participants; p = 0.40), and FSFI scores were not associated with QoL. In multivariable analysis, rural residence (adjusted odds ratio 3.30, 95% CI 1.31–8.98) and primary-level education (aOR 3.06, 95% CI 1.50–6.38) independently predicted poor QoL. Conclusions: Women living with HIV experience poorer overall QoL than HIV-negative peers, particularly in psychological and environmental domains. Interventions that improve living conditions, strengthen psychosocial support and integrate sexual and mental health services into HIV care, are needed to improve the well-being of women in North-western Nigeria. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The interplay of HIV, female sexual dysfunction and quality of life among women in North-western Nigeria: a comparative study.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Damagum%2C+Fatima+M%2E%22&quot;&gt;Damagum, Fatima M.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jalo%2C+Rabiu+I%2E%22&quot;&gt;Jalo, Rabiu I.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ahmed%2C+Zainab+D%2E%22&quot;&gt;Ahmed, Zainab D.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Muhammad%2C+Murtala+A%2E%22&quot;&gt;Muhammad, Murtala A.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Salihu%2C+Hamisu+M%2E%22&quot;&gt;Salihu, Hamisu M.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Maiyaki%2C+Baba+M%2E%22&quot;&gt;Maiyaki, Baba M.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22William%2C+Wester+C%2E%22&quot;&gt;William, Wester C.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Aliyu%2C+Muktar+H%2E%22&quot;&gt;Aliyu, Muktar H.&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22AIDS+Care%22&quot;&gt;AIDS Care&lt;/searchLink&gt;. Feb2026, Vol. 38 Issue 2, p388-395. 8p.
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– Name: Abstract
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  Data: Background: Antiretroviral therapy has markedly increased life expectancy among people living with human immunodeficiency virus (HIV), yet the long-term impact of chronic HIV infection on women&#39;s quality of life (QoL) and sexual functioning remains poorly understood. Female sexual dysfunction (FSD) is common in women and may impair psychological well-being and social relationships. Understanding how HIV infection intersects with FSD and QoL could inform holistic care for women in resource-limited settings. Objective: To compare QoL and FSD between women living with HIV and HIV-negative women and to identify socio-demographic predictors of poor QoL. Methods: We conducted a hospital-based cross-sectional study in 2024 among 200 women on antiretroviral therapy and 200 age-matched HIV-negative women attending the general outpatient clinic at Aminu Kano Teaching Hospital, Kano, Nigeria. Participants were recruited through systematic sampling; research assistants provided study information and obtained written informed consent. Quality of life was assessed with the World Health Organization Quality of Life 26-item Brief questionnaire (WHOQOL-BREF). Female sexual function was screened with the 19-item Female Sexual Function Index (FSFI); a total score ≤26.55 denoted FSD. Data were analyzed using chi-square tests, independent t-tests and multivariable logistic regression. Results: The mean (&#177;SD) age of participants was 37.1 &#177; 9.4 years. Overall QoL was significantly worse among women with HIV than HIV-negative women (53% vs 63% reporting good QoL, p = 0.043). Mean QoL scores were lower in the HIV-positive group for the psychological (61 &#177; 18 vs 54 &#177; 14; p &lt; 0.001) and environmental domains (69 &#177; 20 vs 65 &#177; 16; p &lt; 0.001), while physical and social domain scores were comparable. FSD was highly prevalent in both groups (96% in HIV-positive and 98% in HIV-negative participants; p = 0.40), and FSFI scores were not associated with QoL. In multivariable analysis, rural residence (adjusted odds ratio 3.30, 95% CI 1.31–8.98) and primary-level education (aOR 3.06, 95% CI 1.50–6.38) independently predicted poor QoL. Conclusions: Women living with HIV experience poorer overall QoL than HIV-negative peers, particularly in psychological and environmental domains. Interventions that improve living conditions, strengthen psychosocial support and integrate sexual and mental health services into HIV care, are needed to improve the well-being of women in North-western Nigeria. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: &lt;i&gt;Copyright of AIDS Care is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=191331920
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    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2025.2596817
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      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 388
    Subjects:
      – SubjectFull: Female reproductive organ diseases
        Type: general
      – SubjectFull: Holistic medicine
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Academic medical centers
        Type: general
      – SubjectFull: T-test (Statistics)
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: HIV-positive persons
        Type: general
      – SubjectFull: Multiple regression analysis
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Orgasm
        Type: general
      – SubjectFull: Sexual excitement
        Type: general
      – SubjectFull: Psychology of women
        Type: general
      – SubjectFull: Psychological well-being
        Type: general
      – SubjectFull: Chi-squared test
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Highly active antiretroviral therapy
        Type: general
      – SubjectFull: Sexual dysfunction
        Type: general
      – SubjectFull: Quality of life
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      – SubjectFull: Comparative studies
        Type: general
      – SubjectFull: Interpersonal relations
        Type: general
      – SubjectFull: Resource-limited settings
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Nigeria
        Type: general
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              Text: Feb2026
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