Effect of Cognitive Rehabilitation Nursing on Cognitive Impairment in Patients With Schizophrenia: A Comprehensive Systematic Review and Meta-Analysis.
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| Title: | Effect of Cognitive Rehabilitation Nursing on Cognitive Impairment in Patients With Schizophrenia: A Comprehensive Systematic Review and Meta-Analysis. |
|---|---|
| Authors: | Di, Xin, Yan, Wang, Biao, Li, Tuo, Liu, Jing, Meng |
| Source: | Journal of Cognitive Psychotherapy. 2026, Vol. 40 Issue 1, p52-77. 26p. |
| Subjects: | Diagnosis of schizophrenia, Rehabilitation nursing, Executive function, Treatment effectiveness, Meta-analysis, Systematic reviews, MEDLINE, Cognition disorders, Quality of life, Cognitive therapy, Online information services, Treatment effect heterogeneity, Activities of daily living |
| Abstract: | Cognitive impairment is a core feature of schizophrenia, significantly affecting patients' daily functioning and quality of life. Cognitive rehabilitation nursing (CRN) has emerged as a promising nonpharmacological approach to improve cognitive deficits. This systematic review and meta-analysis aimed to evaluate the efficacy of CRN in enhancing cognitive function in patients with schizophrenia. A systematic literature search was conducted in Web of Science, PubMed, and Scopus for studies published between 2020 and 2025, using a combination of controlled vocabulary and free-text terms. Eligible studies were original, peer-reviewed articles examining CRN interventions in individuals with schizophrenia, with cognitive or functional outcomes. Fifteen studies comprising 19 intervention arms met the inclusion criteria. Methodological quality was assessed using the Cochrane RoB-2 (Risk of Bias 2) tool for randomized trials and ROBINS-I (Risk of Bias in Non-randomized Studies of Interventions) for nonrandomized studies. Standardized mean differences (SMDs) with Hedges' g correction were calculated under a random-effects model. Heterogeneity was examined using I² statistics, and publication bias was evaluated through funnel plots and Egger's test. A total of 19 intervention arms from 15 studies were included. Overall, cognitive rehabilitation yielded a small but favorable effect across cognitive domains (SMD = 0.35, p =.084), with a significant moderate-to-large effect observed for executive function (SMD = 0.63, p =.035), particularly in studies employing computerized, individualized, or virtual reality-based interventions. Effects on global cognition, memory, and functional outcomes were smaller and nonsignificant, while social cognition, assessed in one study, showed a small negative effect (SMD = –0.34, p =.046). Pharmacological and game-based interventions showed inconsistent efficacy. Substantial heterogeneity was present (I² = 85.3%), with outcome domain emerging as a significant moderator (p <.001). Publication bias analysis indicated potential small-study effects, although no missing studies were identified via the trim-and-fill method. This meta-analysis supports the effectiveness of CRN in improving cognitive outcomes in schizophrenia, with the strongest effects on executive function. Targeted, multimodal, and tech-enhanced interventions showed the greatest promise. Despite heterogeneity, the findings were consistent, reinforcing CRN's role in multidisciplinary psychiatric care. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Cognitive Psychotherapy is the property of Springer Publishing Company, Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 191841557 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Effect of Cognitive Rehabilitation Nursing on Cognitive Impairment in Patients With Schizophrenia: A Comprehensive Systematic Review and Meta-Analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Di%2C+Xin%22">Di, Xin</searchLink><br /><searchLink fieldCode="AR" term="%22Yan%2C+Wang%22">Yan, Wang</searchLink><br /><searchLink fieldCode="AR" term="%22Biao%2C+Li%22">Biao, Li</searchLink><br /><searchLink fieldCode="AR" term="%22Tuo%2C+Liu%22">Tuo, Liu</searchLink><br /><searchLink fieldCode="AR" term="%22Jing%2C+Meng%22">Jing, Meng</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Cognitive+Psychotherapy%22">Journal of Cognitive Psychotherapy</searchLink>. 2026, Vol. 40 Issue 1, p52-77. 26p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Diagnosis+of+schizophrenia%22">Diagnosis of schizophrenia</searchLink><br /><searchLink fieldCode="DE" term="%22Rehabilitation+nursing%22">Rehabilitation nursing</searchLink><br /><searchLink fieldCode="DE" term="%22Executive+function%22">Executive function</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Meta-analysis%22">Meta-analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Systematic+reviews%22">Systematic reviews</searchLink><br /><searchLink fieldCode="DE" term="%22MEDLINE%22">MEDLINE</searchLink><br /><searchLink fieldCode="DE" term="%22Cognition+disorders%22">Cognition disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+therapy%22">Cognitive therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Online+information+services%22">Online information services</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effect+heterogeneity%22">Treatment effect heterogeneity</searchLink><br /><searchLink fieldCode="DE" term="%22Activities+of+daily+living%22">Activities of daily living</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Cognitive impairment is a core feature of schizophrenia, significantly affecting patients' daily functioning and quality of life. Cognitive rehabilitation nursing (CRN) has emerged as a promising nonpharmacological approach to improve cognitive deficits. This systematic review and meta-analysis aimed to evaluate the efficacy of CRN in enhancing cognitive function in patients with schizophrenia. A systematic literature search was conducted in Web of Science, PubMed, and Scopus for studies published between 2020 and 2025, using a combination of controlled vocabulary and free-text terms. Eligible studies were original, peer-reviewed articles examining CRN interventions in individuals with schizophrenia, with cognitive or functional outcomes. Fifteen studies comprising 19 intervention arms met the inclusion criteria. Methodological quality was assessed using the Cochrane RoB-2 (Risk of Bias 2) tool for randomized trials and ROBINS-I (Risk of Bias in Non-randomized Studies of Interventions) for nonrandomized studies. Standardized mean differences (SMDs) with Hedges' g correction were calculated under a random-effects model. Heterogeneity was examined using I² statistics, and publication bias was evaluated through funnel plots and Egger's test. A total of 19 intervention arms from 15 studies were included. Overall, cognitive rehabilitation yielded a small but favorable effect across cognitive domains (SMD = 0.35, p =.084), with a significant moderate-to-large effect observed for executive function (SMD = 0.63, p =.035), particularly in studies employing computerized, individualized, or virtual reality-based interventions. Effects on global cognition, memory, and functional outcomes were smaller and nonsignificant, while social cognition, assessed in one study, showed a small negative effect (SMD = –0.34, p =.046). Pharmacological and game-based interventions showed inconsistent efficacy. Substantial heterogeneity was present (I² = 85.3%), with outcome domain emerging as a significant moderator (p <.001). Publication bias analysis indicated potential small-study effects, although no missing studies were identified via the trim-and-fill method. This meta-analysis supports the effectiveness of CRN in improving cognitive outcomes in schizophrenia, with the strongest effects on executive function. Targeted, multimodal, and tech-enhanced interventions showed the greatest promise. Despite heterogeneity, the findings were consistent, reinforcing CRN's role in multidisciplinary psychiatric care. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Cognitive Psychotherapy is the property of Springer Publishing Company, Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1891/JCP-2025-0012 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 26 StartPage: 52 Subjects: – SubjectFull: Diagnosis of schizophrenia Type: general – SubjectFull: Rehabilitation nursing Type: general – SubjectFull: Executive function Type: general – SubjectFull: Treatment effectiveness Type: general – SubjectFull: Meta-analysis Type: general – SubjectFull: Systematic reviews Type: general – SubjectFull: MEDLINE Type: general – SubjectFull: Cognition disorders Type: general – SubjectFull: Quality of life Type: general – SubjectFull: Cognitive therapy Type: general – SubjectFull: Online information services Type: general – SubjectFull: Treatment effect heterogeneity Type: general – SubjectFull: Activities of daily living Type: general Titles: – TitleFull: Effect of Cognitive Rehabilitation Nursing on Cognitive Impairment in Patients With Schizophrenia: A Comprehensive Systematic Review and Meta-Analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Di, Xin – PersonEntity: Name: NameFull: Yan, Wang – PersonEntity: Name: NameFull: Biao, Li – PersonEntity: Name: NameFull: Tuo, Liu – PersonEntity: Name: NameFull: Jing, Meng IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 08898391 Numbering: – Type: volume Value: 40 – Type: issue Value: 1 Titles: – TitleFull: Journal of Cognitive Psychotherapy Type: main |
| ResultId | 1 |
