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The nervous system in early HIV infection: a prospective study through 7 years.

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Title: The nervous system in early HIV infection: a prospective study through 7 years.
Authors: Samuelsson, K., Pirskanen-Matell, R., Bremmer, S., Hindmarsh, T., Nilsson, B. Y., Persson, H. E.
Source: European Journal of Neurology. Mar2006, Vol. 13 Issue 3, p283-291. 9p. 1 Diagram, 3 Charts.
Subjects: HIV infections, Somatosensory evoked potentials, Cerebrospinal fluid, Central nervous system, Electromyography, Neurophysiology
Abstract: In this study 28 patients with early stage HIV infection (CD4 >280 × 106/l) were subjected to yearly examinations of the nervous system up to 7 years in order to detect any deterioration. Clinical neurological as well as neuropsychological performance was evaluated. The patients also underwent yearly neurophysiological tests (digital EEG, visual evoked potentials, somatosensory evoked potentials, auditory evoked potentials P300 and electroneurography). Every other year, SPECT with 99mTc-d,l-hexamethylpropylene amine oxime and brain MRI were performed. Originally, 38 patients were included in the study but only the results of 28 patients who complied with three of more yearly check-ups are presented. The results of yearly investigations of cerebrospinal fluid (CSF) have been presented earlier [ Eur J Neurol 4 (1997) 1]. All the patients showed signs of HIV in the CSF. Yet, no major deterioration in the neurological, psychological performance, neurophysiological or neuroimaging examinations could be discerned. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The nervous system in early HIV infection: a prospective study through 7 years.
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  Data: <searchLink fieldCode="AR" term="%22Samuelsson%2C+K%2E%22">Samuelsson, K.</searchLink><br /><searchLink fieldCode="AR" term="%22Pirskanen-Matell%2C+R%2E%22">Pirskanen-Matell, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Bremmer%2C+S%2E%22">Bremmer, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Hindmarsh%2C+T%2E%22">Hindmarsh, T.</searchLink><br /><searchLink fieldCode="AR" term="%22Nilsson%2C+B%2E+Y%2E%22">Nilsson, B. Y.</searchLink><br /><searchLink fieldCode="AR" term="%22Persson%2C+H%2E+E%2E%22">Persson, H. E.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neurology%22">European Journal of Neurology</searchLink>. Mar2006, Vol. 13 Issue 3, p283-291. 9p. 1 Diagram, 3 Charts.
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  Data: <searchLink fieldCode="DE" term="%22HIV+infections%22">HIV infections</searchLink><br /><searchLink fieldCode="DE" term="%22Somatosensory+evoked+potentials%22">Somatosensory evoked potentials</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebrospinal+fluid%22">Cerebrospinal fluid</searchLink><br /><searchLink fieldCode="DE" term="%22Central+nervous+system%22">Central nervous system</searchLink><br /><searchLink fieldCode="DE" term="%22Electromyography%22">Electromyography</searchLink><br /><searchLink fieldCode="DE" term="%22Neurophysiology%22">Neurophysiology</searchLink>
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  Data: In this study 28 patients with early stage HIV infection (CD4 >280 × 106/l) were subjected to yearly examinations of the nervous system up to 7 years in order to detect any deterioration. Clinical neurological as well as neuropsychological performance was evaluated. The patients also underwent yearly neurophysiological tests (digital EEG, visual evoked potentials, somatosensory evoked potentials, auditory evoked potentials P300 and electroneurography). Every other year, SPECT with 99mTc-d,l-hexamethylpropylene amine oxime and brain MRI were performed. Originally, 38 patients were included in the study but only the results of 28 patients who complied with three of more yearly check-ups are presented. The results of yearly investigations of cerebrospinal fluid (CSF) have been presented earlier [ Eur J Neurol 4 (1997) 1]. All the patients showed signs of HIV in the CSF. Yet, no major deterioration in the neurological, psychological performance, neurophysiological or neuroimaging examinations could be discerned. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=20263222
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        Value: 10.1111/j.1468-1331.2006.01173.x
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        Type: general
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      – SubjectFull: Cerebrospinal fluid
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              Text: Mar2006
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