Effect of disrupted-in-schizophrenia-1 on pre-frontal cortical function.
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| Title: | Effect of disrupted-in-schizophrenia-1 on pre-frontal cortical function. |
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| Authors: | Prata, D P, Mechelli, A, Fu, C H Y, Picchioni, M, Kane, F, Kalidindi, S, McDonald, C, Kravariti, E, Toulopoulou, T, Miorelli, A, Murray, R, Collier, D A, McGuire, P K |
| Source: | Molecular Psychiatry. Oct2008, Vol. 13 Issue 10, p915-917. 3p. 1 Graph. |
| Subjects: | Schizophrenia, Prefrontal cortex, Higher nervous activity, Brain function localization, Psychoses |
| Abstract: | The article discusses a study on how disrupted-in-schizophrenia-1 affects prefrontal cortical function. An analysis of the scans of 53 subjects that consisted of 27 Cys704 carriers and 26 Ser704 homozygotes revealed bilateral activation among all subjects during the verbal fluency task, with Ser704 subjects showing greater activation than Cys704 carriers. It is concluded that the activation in Ser704 subjects was a manifestation of less efficient prefrontal function. |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 34360127 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Effect of disrupted-in-schizophrenia-1 on pre-frontal cortical function. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Prata%2C+D+P%22">Prata, D P</searchLink><br /><searchLink fieldCode="AR" term="%22Mechelli%2C+A%22">Mechelli, A</searchLink><br /><searchLink fieldCode="AR" term="%22Fu%2C+C+H+Y%22">Fu, C H Y</searchLink><br /><searchLink fieldCode="AR" term="%22Picchioni%2C+M%22">Picchioni, M</searchLink><br /><searchLink fieldCode="AR" term="%22Kane%2C+F%22">Kane, F</searchLink><br /><searchLink fieldCode="AR" term="%22Kalidindi%2C+S%22">Kalidindi, S</searchLink><br /><searchLink fieldCode="AR" term="%22McDonald%2C+C%22">McDonald, C</searchLink><br /><searchLink fieldCode="AR" term="%22Kravariti%2C+E%22">Kravariti, E</searchLink><br /><searchLink fieldCode="AR" term="%22Toulopoulou%2C+T%22">Toulopoulou, T</searchLink><br /><searchLink fieldCode="AR" term="%22Miorelli%2C+A%22">Miorelli, A</searchLink><br /><searchLink fieldCode="AR" term="%22Murray%2C+R%22">Murray, R</searchLink><br /><searchLink fieldCode="AR" term="%22Collier%2C+D+A%22">Collier, D A</searchLink><br /><searchLink fieldCode="AR" term="%22McGuire%2C+P+K%22">McGuire, P K</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Molecular+Psychiatry%22">Molecular Psychiatry</searchLink>. Oct2008, Vol. 13 Issue 10, p915-917. 3p. 1 Graph. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Schizophrenia%22">Schizophrenia</searchLink><br /><searchLink fieldCode="DE" term="%22Prefrontal+cortex%22">Prefrontal cortex</searchLink><br /><searchLink fieldCode="DE" term="%22Higher+nervous+activity%22">Higher nervous activity</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+function+localization%22">Brain function localization</searchLink><br /><searchLink fieldCode="DE" term="%22Psychoses%22">Psychoses</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The article discusses a study on how disrupted-in-schizophrenia-1 affects prefrontal cortical function. An analysis of the scans of 53 subjects that consisted of 27 Cys704 carriers and 26 Ser704 homozygotes revealed bilateral activation among all subjects during the verbal fluency task, with Ser704 subjects showing greater activation than Cys704 carriers. It is concluded that the activation in Ser704 subjects was a manifestation of less efficient prefrontal function. |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=34360127 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/mp.2008.76 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 3 StartPage: 915 Subjects: – SubjectFull: Schizophrenia Type: general – SubjectFull: Prefrontal cortex Type: general – SubjectFull: Higher nervous activity Type: general – SubjectFull: Brain function localization Type: general – SubjectFull: Psychoses Type: general Titles: – TitleFull: Effect of disrupted-in-schizophrenia-1 on pre-frontal cortical function. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Prata, D P – PersonEntity: Name: NameFull: Mechelli, A – PersonEntity: Name: NameFull: Fu, C H Y – PersonEntity: Name: NameFull: Picchioni, M – PersonEntity: Name: NameFull: Kane, F – PersonEntity: Name: NameFull: Kalidindi, S – PersonEntity: Name: NameFull: McDonald, C – PersonEntity: Name: NameFull: Kravariti, E – PersonEntity: Name: NameFull: Toulopoulou, T – PersonEntity: Name: NameFull: Miorelli, A – PersonEntity: Name: NameFull: Murray, R – PersonEntity: Name: NameFull: Collier, D A – PersonEntity: Name: NameFull: McGuire, P K IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2008 Type: published Y: 2008 Identifiers: – Type: issn-print Value: 13594184 Numbering: – Type: volume Value: 13 – Type: issue Value: 10 Titles: – TitleFull: Molecular Psychiatry Type: main |
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