Tear ferning in contact lens wearers.
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| Title: | Tear ferning in contact lens wearers. |
|---|---|
| Authors: | Evans, Katharine S. E., North, Rachel V., Purslow, Christine |
| Source: | Ophthalmic & Physiological Optics. Mar2009, Vol. 29 Issue 2, p199-204. 6p. 1 Diagram, 5 Charts, 3 Graphs. |
| Subjects: | Vision research, Contact lenses, Vision disorders, Dry eye syndromes, Microscopy, Etiology of diseases |
| Abstract: | Tear ferning (TF) has shown good sensitivity and specificity in the diagnosis of dry eye, but is a relatively uncommon test, especially in contact lens wearers. The aim of this study was to investigate the relationship between TF, ocular comfort and tear film stability amongst contact lens (CL) wearers and non-contact lens (NCL) wearers. Subjects (36 NCL, 24 CL; mean age 23.2 ± 4.8 years) underwent assessment of non-invasive tear break up time (NIBUT), fluorescein tear break up time (FBUT) and completed the Ocular Comfort Index (OCI) questionnaire. Non-stimulated tears were collected from the inferior tear meniscus with a glass capillary. Samples of 1.5 μL were air dried, observed by light microscopy and the TF pattern quantified according to Rolando’s grading scale. Significantly higher grades of TF pattern and discomfort (higher OCI scores) were observed in CL wearers compared to NCL wearers (Mann–Whitney U-test; p < 0.005 and p < 0.05 respectively). Differences in tear film stability were not significant between groups. Even when asymptomatic (low OCI scores) CL and NCL subjects were compared, TF remained significantly different ( p < 0.005). In both CL and NCL subjects, TF displayed poor correlation with tear film stability tests and OCI scores. Higher TF grades in CL wearers, even if asymptomatic, indicate an unfavourable ratio of salt to macromolecule concentration within the tear film of such subjects. The lack of significant difference in TF between symptomatic CL and NCL wearers could suggest similar aetiology (tear film hyperosmolarity) in each cohort. The TF technique demonstrates limited sensitivity and specificity for the prediction of ocular surface comfort in both CL and NCL wearers. [ABSTRACT FROM AUTHOR] |
| Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 36449605 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Tear ferning in contact lens wearers. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Evans%2C+Katharine+S%2E+E%2E%22">Evans, Katharine S. E.</searchLink><br /><searchLink fieldCode="AR" term="%22North%2C+Rachel+V%2E%22">North, Rachel V.</searchLink><br /><searchLink fieldCode="AR" term="%22Purslow%2C+Christine%22">Purslow, Christine</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Ophthalmic+%26+Physiological+Optics%22">Ophthalmic & Physiological Optics</searchLink>. Mar2009, Vol. 29 Issue 2, p199-204. 6p. 1 Diagram, 5 Charts, 3 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Vision+research%22">Vision research</searchLink><br /><searchLink fieldCode="DE" term="%22Contact+lenses%22">Contact lenses</searchLink><br /><searchLink fieldCode="DE" term="%22Vision+disorders%22">Vision disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Dry+eye+syndromes%22">Dry eye syndromes</searchLink><br /><searchLink fieldCode="DE" term="%22Microscopy%22">Microscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Etiology+of+diseases%22">Etiology of diseases</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Tear ferning (TF) has shown good sensitivity and specificity in the diagnosis of dry eye, but is a relatively uncommon test, especially in contact lens wearers. The aim of this study was to investigate the relationship between TF, ocular comfort and tear film stability amongst contact lens (CL) wearers and non-contact lens (NCL) wearers. Subjects (36 NCL, 24 CL; mean age 23.2 ± 4.8 years) underwent assessment of non-invasive tear break up time (NIBUT), fluorescein tear break up time (FBUT) and completed the Ocular Comfort Index (OCI) questionnaire. Non-stimulated tears were collected from the inferior tear meniscus with a glass capillary. Samples of 1.5 μL were air dried, observed by light microscopy and the TF pattern quantified according to Rolando’s grading scale. Significantly higher grades of TF pattern and discomfort (higher OCI scores) were observed in CL wearers compared to NCL wearers (Mann–Whitney U-test; p < 0.005 and p < 0.05 respectively). Differences in tear film stability were not significant between groups. Even when asymptomatic (low OCI scores) CL and NCL subjects were compared, TF remained significantly different ( p < 0.005). In both CL and NCL subjects, TF displayed poor correlation with tear film stability tests and OCI scores. Higher TF grades in CL wearers, even if asymptomatic, indicate an unfavourable ratio of salt to macromolecule concentration within the tear film of such subjects. The lack of significant difference in TF between symptomatic CL and NCL wearers could suggest similar aetiology (tear film hyperosmolarity) in each cohort. The TF technique demonstrates limited sensitivity and specificity for the prediction of ocular surface comfort in both CL and NCL wearers. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/j.1475-1313.2008.00626.x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 199 Subjects: – SubjectFull: Vision research Type: general – SubjectFull: Contact lenses Type: general – SubjectFull: Vision disorders Type: general – SubjectFull: Dry eye syndromes Type: general – SubjectFull: Microscopy Type: general – SubjectFull: Etiology of diseases Type: general Titles: – TitleFull: Tear ferning in contact lens wearers. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Evans, Katharine S. E. – PersonEntity: Name: NameFull: North, Rachel V. – PersonEntity: Name: NameFull: Purslow, Christine IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: Mar2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 02755408 Numbering: – Type: volume Value: 29 – Type: issue Value: 2 Titles: – TitleFull: Ophthalmic & Physiological Optics Type: main |
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