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Ten years single institutional experience of treatment for advanced laryngeal cancer in Kyoto University.

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Title: Ten years single institutional experience of treatment for advanced laryngeal cancer in Kyoto University.
Authors: Kada, Shinpei, Hirano, Shigeru, Tateya, Ichiro, Kitamura, Morimasa, Ishikawa, Seiji, Kanda, Tomoko, Asato, Ryo, Tanaka, Shinzo, Ito, Juichi
Source: Acta Oto-Laryngologica (Supplement). Nov2010 Supplement 563, Vol. 130, p68-73. 6p. 7 Charts, 3 Graphs.
Subjects: Glottis, Academic medical centers, Analysis of variance, Laryngectomy, Metastasis, Laryngeal cancer, Health outcome assessment, Squamous cell carcinoma, Survival analysis (Biometry), Survival, Treatment effectiveness, Retrospective studies, Classification, Radiotherapy, Drug therapy, Prognosis, Surgery
Geographic Terms: Japan
Abstract: Conclusion: It is important to suppress lymph node recurrence and distant metastasis to achieve better survival of advanced laryngeal cancer, especially supraglottic cancer. Objective: The therapeutic outcomes of 33 cases with advanced laryngeal cancer treated at Kyoto University Hospital between 2000 and 2008 were reviewed. Methods: Thirty-one males and two females were involved. Their ages ranged from 49 to 81 years (average 65.6 years). All tumors were squamous cell carcinoma, arising at the glottis in 21 cases and the supraglottis in 12 cases. Most glottic cancers (90.5%) and supraglottic cancers (83.3%) were classified as T3 or T4. Total laryngectomy with neck dissection was performed in the treatment of T3 or T4 cases. Two cases of T2 cancers were treated by radiotherapy (66-72 Gy) with neck dissection, and one case of T2 cancer was treated by radiotherapy (66 Gy). Partial laryngectomy with neck dissection was performed in one T3 case. Results: Five-year overall survival rates for stage III of glottic cancer, stage IV of glottic cancer, stage III of supraglottic cancer, and stage IV of supraglottic cancer were 100%, 40.9%, 100%, and 24.2%, respectively. Five-year disease-specific survival rates for stage III of glottic cancer, stage IV of glottic cancer, stage III of supraglottic cancer, and stage IV of supraglottic cancer were 100%, 56.3%, 100%, and 28.1%, respectively. No local recurrence occurred. Regional lymph node recurrence occurred in two cases- one patient with glottic cancer and one with supraglottic cancer. Both of them died of disease despite undergoing chemotherapy. One case initially had lung metastasis, and post-treatment distant metastasis occurred in the lung in four cases, in the skin in one, and in multiple organs in one case. [ABSTRACT FROM AUTHOR]
Copyright of Acta Oto-Laryngologica (Supplement) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Ten years single institutional experience of treatment for advanced laryngeal cancer in Kyoto University.
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  Data: <searchLink fieldCode="AR" term="%22Kada%2C+Shinpei%22">Kada, Shinpei</searchLink><br /><searchLink fieldCode="AR" term="%22Hirano%2C+Shigeru%22">Hirano, Shigeru</searchLink><br /><searchLink fieldCode="AR" term="%22Tateya%2C+Ichiro%22">Tateya, Ichiro</searchLink><br /><searchLink fieldCode="AR" term="%22Kitamura%2C+Morimasa%22">Kitamura, Morimasa</searchLink><br /><searchLink fieldCode="AR" term="%22Ishikawa%2C+Seiji%22">Ishikawa, Seiji</searchLink><br /><searchLink fieldCode="AR" term="%22Kanda%2C+Tomoko%22">Kanda, Tomoko</searchLink><br /><searchLink fieldCode="AR" term="%22Asato%2C+Ryo%22">Asato, Ryo</searchLink><br /><searchLink fieldCode="AR" term="%22Tanaka%2C+Shinzo%22">Tanaka, Shinzo</searchLink><br /><searchLink fieldCode="AR" term="%22Ito%2C+Juichi%22">Ito, Juichi</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Acta+Oto-Laryngologica+%28Supplement%29%22">Acta Oto-Laryngologica (Supplement)</searchLink>. Nov2010 Supplement 563, Vol. 130, p68-73. 6p. 7 Charts, 3 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Glottis%22">Glottis</searchLink><br /><searchLink fieldCode="DE" term="%22Academic+medical+centers%22">Academic medical centers</searchLink><br /><searchLink fieldCode="DE" term="%22Analysis+of+variance%22">Analysis of variance</searchLink><br /><searchLink fieldCode="DE" term="%22Laryngectomy%22">Laryngectomy</searchLink><br /><searchLink fieldCode="DE" term="%22Metastasis%22">Metastasis</searchLink><br /><searchLink fieldCode="DE" term="%22Laryngeal+cancer%22">Laryngeal cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Health+outcome+assessment%22">Health outcome assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Squamous+cell+carcinoma%22">Squamous cell carcinoma</searchLink><br /><searchLink fieldCode="DE" term="%22Survival+analysis+%28Biometry%29%22">Survival analysis (Biometry)</searchLink><br /><searchLink fieldCode="DE" term="%22Survival%22">Survival</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Retrospective+studies%22">Retrospective studies</searchLink><br /><searchLink fieldCode="DE" term="%22Classification%22">Classification</searchLink><br /><searchLink fieldCode="DE" term="%22Radiotherapy%22">Radiotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+therapy%22">Drug therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Prognosis%22">Prognosis</searchLink><br /><searchLink fieldCode="DE" term="%22Surgery%22">Surgery</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Japan%22">Japan</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Conclusion: It is important to suppress lymph node recurrence and distant metastasis to achieve better survival of advanced laryngeal cancer, especially supraglottic cancer. Objective: The therapeutic outcomes of 33 cases with advanced laryngeal cancer treated at Kyoto University Hospital between 2000 and 2008 were reviewed. Methods: Thirty-one males and two females were involved. Their ages ranged from 49 to 81 years (average 65.6 years). All tumors were squamous cell carcinoma, arising at the glottis in 21 cases and the supraglottis in 12 cases. Most glottic cancers (90.5%) and supraglottic cancers (83.3%) were classified as T3 or T4. Total laryngectomy with neck dissection was performed in the treatment of T3 or T4 cases. Two cases of T2 cancers were treated by radiotherapy (66-72 Gy) with neck dissection, and one case of T2 cancer was treated by radiotherapy (66 Gy). Partial laryngectomy with neck dissection was performed in one T3 case. Results: Five-year overall survival rates for stage III of glottic cancer, stage IV of glottic cancer, stage III of supraglottic cancer, and stage IV of supraglottic cancer were 100%, 40.9%, 100%, and 24.2%, respectively. Five-year disease-specific survival rates for stage III of glottic cancer, stage IV of glottic cancer, stage III of supraglottic cancer, and stage IV of supraglottic cancer were 100%, 56.3%, 100%, and 28.1%, respectively. No local recurrence occurred. Regional lymph node recurrence occurred in two cases- one patient with glottic cancer and one with supraglottic cancer. Both of them died of disease despite undergoing chemotherapy. One case initially had lung metastasis, and post-treatment distant metastasis occurred in the lung in four cases, in the skin in one, and in multiple organs in one case. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Oto-Laryngologica (Supplement) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.3109/00016489.2010.492237
    Languages:
      – Code: eng
        Text: English
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        PageCount: 6
        StartPage: 68
    Subjects:
      – SubjectFull: Glottis
        Type: general
      – SubjectFull: Academic medical centers
        Type: general
      – SubjectFull: Analysis of variance
        Type: general
      – SubjectFull: Laryngectomy
        Type: general
      – SubjectFull: Metastasis
        Type: general
      – SubjectFull: Laryngeal cancer
        Type: general
      – SubjectFull: Health outcome assessment
        Type: general
      – SubjectFull: Squamous cell carcinoma
        Type: general
      – SubjectFull: Survival analysis (Biometry)
        Type: general
      – SubjectFull: Survival
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      – SubjectFull: Treatment effectiveness
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      – SubjectFull: Retrospective studies
        Type: general
      – SubjectFull: Classification
        Type: general
      – SubjectFull: Radiotherapy
        Type: general
      – SubjectFull: Drug therapy
        Type: general
      – SubjectFull: Prognosis
        Type: general
      – SubjectFull: Surgery
        Type: general
      – SubjectFull: Japan
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      – TitleFull: Ten years single institutional experience of treatment for advanced laryngeal cancer in Kyoto University.
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              M: 11
              Text: Nov2010 Supplement 563
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