View in EDS HTML Full Text PDF Full Text

Effects of alcohol consumption on iron metabolism.

Saved in:
Bibliographic Details
Title: Effects of alcohol consumption on iron metabolism.
Authors: Lieb, M. (AUTHOR), Palm, U. (AUTHOR), Hock, B. (AUTHOR), Schwarz, M. (AUTHOR), Domke, I. (AUTHOR), Soyka, M. (AUTHOR)
Source: American Journal of Drug & Alcohol Abuse. 2011, Vol. 37 Issue 1, p68-73. 6p. 3 Charts, 2 Graphs.
Subjects: Physiological effects of alcohol, Malnutrition, Iron metabolism, Ferritin, Transferrin, C-reactive protein, Folic acid in human nutrition, Blood diseases, Vitamin B complex, Physiology
Abstract: Background//objectives: Patients with alcohol abuse frequently suffer from malnutrition which may result in insufficient iron distribution and iron overload or deficiency. Iron metabolism can be described by a combination of biochemical soluble transferrin receptor, ferritin, C-reactive protein (CRP), and hematological parameters. Here, vitamin B12 and folic acid state were assessed. Results on iron metabolism in patients with alcohol dependence in comparison with social drinkers are presented. Materials//methods: Samples from 101 patients with dependent alcohol consumption were included. The control group comprised 115 social drinkers. Inclusion criteria for patients with chronic regular drinking//social drinkers were positive//negative score of the Alcohol Use Disorders Identification Test (AUDIT), and positive//negative score for alcohol abuse//dependence (DSM-IV criteria). Results: Absolute values for ferritin and sTfR are increased in patients with alcohol dependence with current consumption (ALC) compared with social drinkers. No major differences are observed in the ratio of sTfR//log ferritin in comparison with social drinkers. Hemoglobin concentrations correlated between the two groups. Mean corpuscular volume (MCV) was significantly increased in the ALC collective compared to social drinkers. Eighty patients of the alcohol-dependent group had sufficient iron repletion, 11 had iron overload, 6 are suspicious for functional iron deficiency, and 4 are suspicious for reduced iron supply. No vitamin B12//folate deficiencies are observed in alcohol-dependent patients. Conclusions and Scientific Significance: No major abnormalities of iron metabolism are seen in patients with chronic alcohol ingestion besides the well-known macrocytic anemia. Iron overload is relatively frequent and observed in 9%% of cases. No differences in vitamin B12 and folate levels were found between individuals with alcohol dependence and social drinkers. [ABSTRACT FROM AUTHOR]
Copyright of American Journal of Drug & Alcohol Abuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 57821829
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Effects of alcohol consumption on iron metabolism.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Lieb%2C+M%2E%22">Lieb, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Palm%2C+U%2E%22">Palm, U.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hock%2C+B%2E%22">Hock, B.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Schwarz%2C+M%2E%22">Schwarz, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Domke%2C+I%2E%22">Domke, I.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Soyka%2C+M%2E%22">Soyka, M.</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22American+Journal+of+Drug+%26+Alcohol+Abuse%22">American Journal of Drug & Alcohol Abuse</searchLink>. 2011, Vol. 37 Issue 1, p68-73. 6p. 3 Charts, 2 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Physiological+effects+of+alcohol%22">Physiological effects of alcohol</searchLink><br /><searchLink fieldCode="DE" term="%22Malnutrition%22">Malnutrition</searchLink><br /><searchLink fieldCode="DE" term="%22Iron+metabolism%22">Iron metabolism</searchLink><br /><searchLink fieldCode="DE" term="%22Ferritin%22">Ferritin</searchLink><br /><searchLink fieldCode="DE" term="%22Transferrin%22">Transferrin</searchLink><br /><searchLink fieldCode="DE" term="%22C-reactive+protein%22">C-reactive protein</searchLink><br /><searchLink fieldCode="DE" term="%22Folic+acid+in+human+nutrition%22">Folic acid in human nutrition</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+diseases%22">Blood diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Vitamin+B+complex%22">Vitamin B complex</searchLink><br /><searchLink fieldCode="DE" term="%22Physiology%22">Physiology</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background//objectives: Patients with alcohol abuse frequently suffer from malnutrition which may result in insufficient iron distribution and iron overload or deficiency. Iron metabolism can be described by a combination of biochemical soluble transferrin receptor, ferritin, C-reactive protein (CRP), and hematological parameters. Here, vitamin B12 and folic acid state were assessed. Results on iron metabolism in patients with alcohol dependence in comparison with social drinkers are presented. Materials//methods: Samples from 101 patients with dependent alcohol consumption were included. The control group comprised 115 social drinkers. Inclusion criteria for patients with chronic regular drinking//social drinkers were positive//negative score of the Alcohol Use Disorders Identification Test (AUDIT), and positive//negative score for alcohol abuse//dependence (DSM-IV criteria). Results: Absolute values for ferritin and sTfR are increased in patients with alcohol dependence with current consumption (ALC) compared with social drinkers. No major differences are observed in the ratio of sTfR//log ferritin in comparison with social drinkers. Hemoglobin concentrations correlated between the two groups. Mean corpuscular volume (MCV) was significantly increased in the ALC collective compared to social drinkers. Eighty patients of the alcohol-dependent group had sufficient iron repletion, 11 had iron overload, 6 are suspicious for functional iron deficiency, and 4 are suspicious for reduced iron supply. No vitamin B12//folate deficiencies are observed in alcohol-dependent patients. Conclusions and Scientific Significance: No major abnormalities of iron metabolism are seen in patients with chronic alcohol ingestion besides the well-known macrocytic anemia. Iron overload is relatively frequent and observed in 9%% of cases. No differences in vitamin B12 and folate levels were found between individuals with alcohol dependence and social drinkers. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of American Journal of Drug & Alcohol Abuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=57821829
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3109/00952990.2010.535584
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 6
        StartPage: 68
    Subjects:
      – SubjectFull: Physiological effects of alcohol
        Type: general
      – SubjectFull: Malnutrition
        Type: general
      – SubjectFull: Iron metabolism
        Type: general
      – SubjectFull: Ferritin
        Type: general
      – SubjectFull: Transferrin
        Type: general
      – SubjectFull: C-reactive protein
        Type: general
      – SubjectFull: Folic acid in human nutrition
        Type: general
      – SubjectFull: Blood diseases
        Type: general
      – SubjectFull: Vitamin B complex
        Type: general
      – SubjectFull: Physiology
        Type: general
    Titles:
      – TitleFull: Effects of alcohol consumption on iron metabolism.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Lieb, M.
      – PersonEntity:
          Name:
            NameFull: Palm, U.
      – PersonEntity:
          Name:
            NameFull: Hock, B.
      – PersonEntity:
          Name:
            NameFull: Schwarz, M.
      – PersonEntity:
          Name:
            NameFull: Domke, I.
      – PersonEntity:
          Name:
            NameFull: Soyka, M.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: 2011
              Type: published
              Y: 2011
          Identifiers:
            – Type: issn-print
              Value: 00952990
          Numbering:
            – Type: volume
              Value: 37
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: American Journal of Drug & Alcohol Abuse
              Type: main
ResultId 1