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Serum Folate and B12 and Haematological Status of In-patient Alcoholics.

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Title: Serum Folate and B12 and Haematological Status of In-patient Alcoholics.
Authors: Carney, M.W.P., Sheffield, B.
Source: British Journal of Addiction (to Alcohol & Other Drugs). Mar78, Vol. 73 Issue 1, p3-7. 5p.
Subjects: People with alcoholism, Alcoholism, Serum, Vitamin B12, Blood, Hospital care
Abstract: During 1972 and 1973, 33 alcoholic in-patients, probably representative of alcoholism of more than 3years duration in a predominantly urban population of 310,000, were investigated. Data relating to serum folate and B12 values, and haemoglobin, red and white blood count, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration, were obtained and compared with similar findings from 239 patients with other psychiatric conditions admitted over the same period. The groups did not differ significantly with respect to mean folate or B12, but there were significantly more folate values greater than 4.9 ng/ml among the alcoholics than among the other patients. Twenty four percent of alcoholics and other patients were malnourished. The mean folate of the malnourished alcoholics was significantly lower than that of the adequately nourished alcoholics. Significantly more alcoholics than other patients showed low RBC, macrocytosis and high MCH. Macrocytosis among the alcoholics was not satisfactorily accounted for by low folate and B12, or hepatic dysfunction. Sixty seven percent of the alcoholics were macrocytic, and seventy five percent had maerocytosis and/or elevated MCH. It was felt that the data were consistent with impaired haemapoiesis in alcoholism and that MC V and MCH were useful pointers to the diagnosis. [ABSTRACT FROM AUTHOR]
Copyright of British Journal of Addiction (to Alcohol & Other Drugs) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Serum Folate and B12 and Haematological Status of In-patient Alcoholics.
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  Data: <searchLink fieldCode="AR" term="%22Carney%2C+M%2EW%2EP%2E%22">Carney, M.W.P.</searchLink><br /><searchLink fieldCode="AR" term="%22Sheffield%2C+B%2E%22">Sheffield, B.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22British+Journal+of+Addiction+%28to+Alcohol+%26+Other+Drugs%29%22">British Journal of Addiction (to Alcohol & Other Drugs)</searchLink>. Mar78, Vol. 73 Issue 1, p3-7. 5p.
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  Data: <searchLink fieldCode="DE" term="%22People+with+alcoholism%22">People with alcoholism</searchLink><br /><searchLink fieldCode="DE" term="%22Alcoholism%22">Alcoholism</searchLink><br /><searchLink fieldCode="DE" term="%22Serum%22">Serum</searchLink><br /><searchLink fieldCode="DE" term="%22Vitamin+B12%22">Vitamin B12</searchLink><br /><searchLink fieldCode="DE" term="%22Blood%22">Blood</searchLink><br /><searchLink fieldCode="DE" term="%22Hospital+care%22">Hospital care</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: During 1972 and 1973, 33 alcoholic in-patients, probably representative of alcoholism of more than 3years duration in a predominantly urban population of 310,000, were investigated. Data relating to serum folate and B12 values, and haemoglobin, red and white blood count, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration, were obtained and compared with similar findings from 239 patients with other psychiatric conditions admitted over the same period. The groups did not differ significantly with respect to mean folate or B12, but there were significantly more folate values greater than 4.9 ng/ml among the alcoholics than among the other patients. Twenty four percent of alcoholics and other patients were malnourished. The mean folate of the malnourished alcoholics was significantly lower than that of the adequately nourished alcoholics. Significantly more alcoholics than other patients showed low RBC, macrocytosis and high MCH. Macrocytosis among the alcoholics was not satisfactorily accounted for by low folate and B12, or hepatic dysfunction. Sixty seven percent of the alcoholics were macrocytic, and seventy five percent had maerocytosis and/or elevated MCH. It was felt that the data were consistent with impaired haemapoiesis in alcoholism and that MC V and MCH were useful pointers to the diagnosis. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of British Journal of Addiction (to Alcohol & Other Drugs) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1111/j.1360-0443.1978.tb00112.x
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      – Code: eng
        Text: English
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        PageCount: 5
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      – SubjectFull: People with alcoholism
        Type: general
      – SubjectFull: Alcoholism
        Type: general
      – SubjectFull: Serum
        Type: general
      – SubjectFull: Vitamin B12
        Type: general
      – SubjectFull: Blood
        Type: general
      – SubjectFull: Hospital care
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      – TitleFull: Serum Folate and B12 and Haematological Status of In-patient Alcoholics.
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              Text: Mar78
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              Y: 1978
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