View in EDS HTML Full Text PDF Full Text

Gene expression of the endolymphatic sac.

Saved in:
Bibliographic Details
Title: Gene expression of the endolymphatic sac.
Authors: Friis, Morten (AUTHOR), Martin-Bertelsen, Tomas (AUTHOR), Friis-Hansen, Lennart (AUTHOR), Winther, Ole (AUTHOR), Henao, Ricardo (AUTHOR), Sørensen, Mads Sølvsten (AUTHOR), Qvortrup, Klaus (AUTHOR)
Source: Acta Oto-Laryngologica. Dec2011, Vol. 131 Issue 12, p1257-1263. 7p. 1 Diagram, 1 Graph.
Subjects: Inner ear physiology, Animal experimentation, Gene expression, Polymerase chain reaction, Rats, RNA, Statistics, T-test (Statistics), Microarray technology
Abstract: Conclusion: The endolymphatic sac is part of the membranous inner ear and is thought to play a role in the fluid homeostasis and immune defense of the inner ear; however, the exact function of the endolymphatic sac is not fully known. Many of the detected mRNAs in this study suggest that the endolymphatic sac has multiple and diverse functions in the inner ear. Objectives:The objective of this study was to provide a comprehensive review of the genes expressed in the endolymphatic sac in the rat and perform a functional characterization based on measured mRNA abundance. Methods:Microarray technology was used to investigate the gene expression of the endolymphatic sac with the surrounding dura. Characteristic and novel endolymphatic sac genes were determined by comparing with expressions in pure dura. Results: In all, 463 genes were identified specific for the endolymphatic sac. Functional annotation clustering revealed 29 functional clusters. [ABSTRACT FROM AUTHOR]
Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 67130942
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Gene expression of the endolymphatic sac.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Friis%2C+Morten%22">Friis, Morten</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Martin-Bertelsen%2C+Tomas%22">Martin-Bertelsen, Tomas</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Friis-Hansen%2C+Lennart%22">Friis-Hansen, Lennart</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Winther%2C+Ole%22">Winther, Ole</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Henao%2C+Ricardo%22">Henao, Ricardo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sørensen%2C+Mads+Sølvsten%22">Sørensen, Mads Sølvsten</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Qvortrup%2C+Klaus%22">Qvortrup, Klaus</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Acta+Oto-Laryngologica%22">Acta Oto-Laryngologica</searchLink>. Dec2011, Vol. 131 Issue 12, p1257-1263. 7p. 1 Diagram, 1 Graph.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Inner+ear+physiology%22">Inner ear physiology</searchLink><br /><searchLink fieldCode="DE" term="%22Animal+experimentation%22">Animal experimentation</searchLink><br /><searchLink fieldCode="DE" term="%22Gene+expression%22">Gene expression</searchLink><br /><searchLink fieldCode="DE" term="%22Polymerase+chain+reaction%22">Polymerase chain reaction</searchLink><br /><searchLink fieldCode="DE" term="%22Rats%22">Rats</searchLink><br /><searchLink fieldCode="DE" term="%22RNA%22">RNA</searchLink><br /><searchLink fieldCode="DE" term="%22Statistics%22">Statistics</searchLink><br /><searchLink fieldCode="DE" term="%22T-test+%28Statistics%29%22">T-test (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Microarray+technology%22">Microarray technology</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Conclusion: The endolymphatic sac is part of the membranous inner ear and is thought to play a role in the fluid homeostasis and immune defense of the inner ear; however, the exact function of the endolymphatic sac is not fully known. Many of the detected mRNAs in this study suggest that the endolymphatic sac has multiple and diverse functions in the inner ear. Objectives:The objective of this study was to provide a comprehensive review of the genes expressed in the endolymphatic sac in the rat and perform a functional characterization based on measured mRNA abundance. Methods:Microarray technology was used to investigate the gene expression of the endolymphatic sac with the surrounding dura. Characteristic and novel endolymphatic sac genes were determined by comparing with expressions in pure dura. Results: In all, 463 genes were identified specific for the endolymphatic sac. Functional annotation clustering revealed 29 functional clusters. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=67130942
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3109/00016489.2011.616910
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 1257
    Subjects:
      – SubjectFull: Inner ear physiology
        Type: general
      – SubjectFull: Animal experimentation
        Type: general
      – SubjectFull: Gene expression
        Type: general
      – SubjectFull: Polymerase chain reaction
        Type: general
      – SubjectFull: Rats
        Type: general
      – SubjectFull: RNA
        Type: general
      – SubjectFull: Statistics
        Type: general
      – SubjectFull: T-test (Statistics)
        Type: general
      – SubjectFull: Microarray technology
        Type: general
    Titles:
      – TitleFull: Gene expression of the endolymphatic sac.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Friis, Morten
      – PersonEntity:
          Name:
            NameFull: Martin-Bertelsen, Tomas
      – PersonEntity:
          Name:
            NameFull: Friis-Hansen, Lennart
      – PersonEntity:
          Name:
            NameFull: Winther, Ole
      – PersonEntity:
          Name:
            NameFull: Henao, Ricardo
      – PersonEntity:
          Name:
            NameFull: Sørensen, Mads Sølvsten
      – PersonEntity:
          Name:
            NameFull: Qvortrup, Klaus
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 12
              Text: Dec2011
              Type: published
              Y: 2011
          Identifiers:
            – Type: issn-print
              Value: 00016489
          Numbering:
            – Type: volume
              Value: 131
            – Type: issue
              Value: 12
          Titles:
            – TitleFull: Acta Oto-Laryngologica
              Type: main
ResultId 1