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Postictal psychosis in temporal lobe epilepsy: a case-control study.

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Title: Postictal psychosis in temporal lobe epilepsy: a case-control study.
Authors: Hilger, E., Zimprich, F., Jung, R., Pataraia, E., Baumgartner, C., Bonelli, S.
Source: European Journal of Neurology. Jun2013, Vol. 20 Issue 6, p955-961. 7p. 3 Charts.
Subjects: Psychoses, Temporal lobe epilepsy, Electroencephalography, Magnetic resonance imaging, Univariate analysis
Abstract: Background and purpose To investigate the prevalence of postictal psychosis ( PP) in patients with temporal lobe epilepsy ( TLE) and to estimate the predictive value of various variables for the development of PP. Methods By retrospectively reviewing the charts of all patients evaluated with video-electroencephalogram ( EEG)-monitoring at our unit between January 1995 and February 2012, we identified 684 patients with TLE, of which 48 patients had a history of PP. Patients with TLE and PP were compared with 200 controls (patients with TLE without a psychotic history) on demographic, clinical, EEG and magnetic resonance imaging ( MRI) variables. Results The prevalence of PP in our TLE sample was 7.0%. Aggressive behaviour during PP was present in 22.9% of the sample. Univariate analysis revealed that PP was significantly associated with early age at epilepsy onset ( P = 0.007), longer duration of epilepsy ( P = 0.002), presence of ictal fear ( P = 0.005), impaired intellectual function ( P = 0.045), and bilateral ictal and interictal epileptiform activity (both P < 0.0001). Using logistic regression analysis, ictal fear [odds ratio ( OR) 2.88; P = 0.015] and bilateral interictal EEG activity ( OR 6.40; P < 0.0001) were predictive of PP development. No association of PP with MRI pathology or epilepsy-relevant aetiological factors was found. Conclusions PP is a frequent and potentially dangerous complication within the course of TLE. Bilateral or widespread functional central nervous system disturbances rather than distinct structural brain alterations or certain predisposing aetiologies of epilepsy appear to be a risk factor for the development of PP. Ictal fear may be a predictive clinical variable of PP in TLE. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Postictal psychosis in temporal lobe epilepsy: a case-control study.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hilger%2C+E%2E%22&quot;&gt;Hilger, E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Zimprich%2C+F%2E%22&quot;&gt;Zimprich, F.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jung%2C+R%2E%22&quot;&gt;Jung, R.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pataraia%2C+E%2E%22&quot;&gt;Pataraia, E.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Baumgartner%2C+C%2E%22&quot;&gt;Baumgartner, C.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Bonelli%2C+S%2E%22&quot;&gt;Bonelli, S.&lt;/searchLink&gt;
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Journal+of+Neurology%22&quot;&gt;European Journal of Neurology&lt;/searchLink&gt;. Jun2013, Vol. 20 Issue 6, p955-961. 7p. 3 Charts.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Psychoses%22&quot;&gt;Psychoses&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Temporal+lobe+epilepsy%22&quot;&gt;Temporal lobe epilepsy&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Electroencephalography%22&quot;&gt;Electroencephalography&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Magnetic+resonance+imaging%22&quot;&gt;Magnetic resonance imaging&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Univariate+analysis%22&quot;&gt;Univariate analysis&lt;/searchLink&gt;
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  Data: Background and purpose To investigate the prevalence of postictal psychosis ( PP) in patients with temporal lobe epilepsy ( TLE) and to estimate the predictive value of various variables for the development of PP. Methods By retrospectively reviewing the charts of all patients evaluated with video-electroencephalogram ( EEG)-monitoring at our unit between January 1995 and February 2012, we identified 684 patients with TLE, of which 48 patients had a history of PP. Patients with TLE and PP were compared with 200 controls (patients with TLE without a psychotic history) on demographic, clinical, EEG and magnetic resonance imaging ( MRI) variables. Results The prevalence of PP in our TLE sample was 7.0%. Aggressive behaviour during PP was present in 22.9% of the sample. Univariate analysis revealed that PP was significantly associated with early age at epilepsy onset ( P = 0.007), longer duration of epilepsy ( P = 0.002), presence of ictal fear ( P = 0.005), impaired intellectual function ( P = 0.045), and bilateral ictal and interictal epileptiform activity (both P &lt; 0.0001). Using logistic regression analysis, ictal fear [odds ratio ( OR) 2.88; P = 0.015] and bilateral interictal EEG activity ( OR 6.40; P &lt; 0.0001) were predictive of PP development. No association of PP with MRI pathology or epilepsy-relevant aetiological factors was found. Conclusions PP is a frequent and potentially dangerous complication within the course of TLE. Bilateral or widespread functional central nervous system disturbances rather than distinct structural brain alterations or certain predisposing aetiologies of epilepsy appear to be a risk factor for the development of PP. Ictal fear may be a predictive clinical variable of PP in TLE. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1111/ene.12125
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        Text: English
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        PageCount: 7
        StartPage: 955
    Subjects:
      – SubjectFull: Psychoses
        Type: general
      – SubjectFull: Temporal lobe epilepsy
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      – SubjectFull: Electroencephalography
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      – SubjectFull: Magnetic resonance imaging
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      – SubjectFull: Univariate analysis
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      – TitleFull: Postictal psychosis in temporal lobe epilepsy: a case-control study.
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            NameFull: Hilger, E.
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              Text: Jun2013
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              Y: 2013
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