View in EDS PDF Full Text

Modulation of trigeminal reflex excitability in migraine: effects of attention and habituation on the blink reflex.

Saved in:
Bibliographic Details
Title: Modulation of trigeminal reflex excitability in migraine: effects of attention and habituation on the blink reflex.
Authors: de Tommaso, M, Murasecco, D, Libro, G, Guido, M, Sciruicchio, V, Specchio, LM, Gallai, V, Puca, F
Source: Headache: The Journal of Head & Face Pain. Mar2003, Vol. 43 Issue 3, p303-303. 1p.
Subjects: Migraine, Excitation (Physiology), Reflexes
Abstract: Int J Psychophysiol . 2002 Jun;44(3):239-249 The modulation of trigeminal reflex excitability in migraine patients was evaluated during the asymptomatic phase by studying the effects of attention, habituation and preconditioning stimulus on the R2 and R3 components of the blink reflex (BR). Fifty patients suffering from migraine without aura, 20 affected by migraine with aura and 35 sex- and age-matched controls were selected. In subgroups of migraine with-aura and without-aura patients, and normal controls, the blink reflex was elicited during different cognitive situations: (a) spontaneous mental activity; (b) stimulus anticipation; (c) recognition of target numbers. In the remaining subjects, R2 and R3 habituation was evaluated by repetitive stimulation at 1, 5, 10, 15, 20, 25 and 30 s intervals. The R2 and R3 recovery curves were also computed. A reduced R3 threshold with a normal pain threshold was found in migraine with-aura and without-aura patients; the R3 component was not significantly correlated with the pain thresholds in patients and controls. The R2 and R3 components were less influenced by the warning of the stimulus in migraine without-aura and migraine with-aura patients, in comparison with the control group. A slight increase of both R2 and R3 recovery after preconditioning stimulus was also observed in migraine patients, probably caused by a phenomenon of trigeminal hyperexcitability persisting after the last attack. The abnormal BR modulation by alerting expresses in migraine a dysfunction of adaptation capacity to environmental conditions, probably predisposing to migraine. Comment: Further physiologic and functional evidence for the interictal hyperexcitability of neurons in patients with migraine, in this case trigeminal neurons involved in the blink reflex. SJT. [ABSTRACT FROM AUTHOR]
Copyright of Headache: The Journal of Head & Face Pain is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 9121647
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Modulation of trigeminal reflex excitability in migraine: effects of attention and habituation on the blink reflex.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22de+Tommaso%2C+M%22">de Tommaso, M</searchLink><br /><searchLink fieldCode="AR" term="%22Murasecco%2C+D%22">Murasecco, D</searchLink><br /><searchLink fieldCode="AR" term="%22Libro%2C+G%22">Libro, G</searchLink><br /><searchLink fieldCode="AR" term="%22Guido%2C+M%22">Guido, M</searchLink><br /><searchLink fieldCode="AR" term="%22Sciruicchio%2C+V%22">Sciruicchio, V</searchLink><br /><searchLink fieldCode="AR" term="%22Specchio%2C+LM%22">Specchio, LM</searchLink><br /><searchLink fieldCode="AR" term="%22Gallai%2C+V%22">Gallai, V</searchLink><br /><searchLink fieldCode="AR" term="%22Puca%2C+F%22">Puca, F</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Headache%3A+The+Journal+of+Head+%26+Face+Pain%22">Headache: The Journal of Head & Face Pain</searchLink>. Mar2003, Vol. 43 Issue 3, p303-303. 1p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Migraine%22">Migraine</searchLink><br /><searchLink fieldCode="DE" term="%22Excitation+%28Physiology%29%22">Excitation (Physiology)</searchLink><br /><searchLink fieldCode="DE" term="%22Reflexes%22">Reflexes</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Int J Psychophysiol . 2002 Jun;44(3):239-249 The modulation of trigeminal reflex excitability in migraine patients was evaluated during the asymptomatic phase by studying the effects of attention, habituation and preconditioning stimulus on the R2 and R3 components of the blink reflex (BR). Fifty patients suffering from migraine without aura, 20 affected by migraine with aura and 35 sex- and age-matched controls were selected. In subgroups of migraine with-aura and without-aura patients, and normal controls, the blink reflex was elicited during different cognitive situations: (a) spontaneous mental activity; (b) stimulus anticipation; (c) recognition of target numbers. In the remaining subjects, R2 and R3 habituation was evaluated by repetitive stimulation at 1, 5, 10, 15, 20, 25 and 30 s intervals. The R2 and R3 recovery curves were also computed. A reduced R3 threshold with a normal pain threshold was found in migraine with-aura and without-aura patients; the R3 component was not significantly correlated with the pain thresholds in patients and controls. The R2 and R3 components were less influenced by the warning of the stimulus in migraine without-aura and migraine with-aura patients, in comparison with the control group. A slight increase of both R2 and R3 recovery after preconditioning stimulus was also observed in migraine patients, probably caused by a phenomenon of trigeminal hyperexcitability persisting after the last attack. The abnormal BR modulation by alerting expresses in migraine a dysfunction of adaptation capacity to environmental conditions, probably predisposing to migraine. Comment: Further physiologic and functional evidence for the interictal hyperexcitability of neurons in patients with migraine, in this case trigeminal neurons involved in the blink reflex. SJT. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Headache: The Journal of Head & Face Pain is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=9121647
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1046/j.1526-4610.2003.03062_10.x
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: 303
    Subjects:
      – SubjectFull: Migraine
        Type: general
      – SubjectFull: Excitation (Physiology)
        Type: general
      – SubjectFull: Reflexes
        Type: general
    Titles:
      – TitleFull: Modulation of trigeminal reflex excitability in migraine: effects of attention and habituation on the blink reflex.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: de Tommaso, M
      – PersonEntity:
          Name:
            NameFull: Murasecco, D
      – PersonEntity:
          Name:
            NameFull: Libro, G
      – PersonEntity:
          Name:
            NameFull: Guido, M
      – PersonEntity:
          Name:
            NameFull: Sciruicchio, V
      – PersonEntity:
          Name:
            NameFull: Specchio, LM
      – PersonEntity:
          Name:
            NameFull: Gallai, V
      – PersonEntity:
          Name:
            NameFull: Puca, F
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2003
              Type: published
              Y: 2003
          Identifiers:
            – Type: issn-print
              Value: 00178748
          Numbering:
            – Type: volume
              Value: 43
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Headache: The Journal of Head & Face Pain
              Type: main
ResultId 1