External hemorrhages derived from traumas caused by armed conflicts, road accidents and daily incidents are “increasingly frequent and represent 9% of annual mortality in the world, it is considered that hemorrhage is responsible for 30 to 40% of these deaths” (Mejia Mantilla, Puentes Manosalva, Cir...
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https://revistas.sena.edu.co/index.php/sennova/article/view/5361 |
| Summary: | External hemorrhages derived from traumas caused by armed conflicts, road accidents and daily incidents are “increasingly frequent and represent 9% of annual mortality in the world, it is considered that hemorrhage is responsible for 30 to 40% of these deaths” (Mejia Mantilla, Puentes Manosalva, Ciro, & Morales, 2009). This encouraged the group of researchers to identify the scenarios of use and effectiveness of available hemostatic agents through a literature review; Key concepts in English and Spanish were taken into account for the search in databases, such as Pubmed, Lilacs, Scopus and Science Direct, in which methods, drugs, devices and pharmaceutical forms that are used for control were found. of hemorrhages. In a conglomerate and information processing, an analysis table was carried out in Microsoft Excel where 64 national and international documents on the use of hemostatic agents in the civil and military environment were included. These were classified according to their active ingredients, biomedical technology, mechanisms of action, hemostatic effects, material source, use scenarios, and effectiveness. It was concluded that defining the active ingredient based on the source of the material, for a future development of a hemostatic agent, will facilitate its availability and access, on the other hand, the education and training in the use of hemostatic agents and hemostatic biotechnological implementation, could influence the ease and access to them, these aspects could contribute to the reduction of morbidity and mortality in patients with external bleeding |
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