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Fulcrum Occupancy–Leverage Perturbation Strategy Enables Rapid Discovery of Potent CDK2–Cyclin A2 Interaction Inhibitors.

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Title: Fulcrum Occupancy–Leverage Perturbation Strategy Enables Rapid Discovery of Potent CDK2–Cyclin A2 Interaction Inhibitors.
Authors: Sun, Ge1,2, Chi, Shuaishuai1,3, Li, Jiacheng1,2, Xu, Pan1,2, Lin, Tingting2, Chen, Chao1,4, Liu, Liping1,2, Yang, Yulin1,2, Yan, Ruyu1,2,5, Han, HongBo1,2, Wang, Mingyu1,2, Fu, Shuiping1,2, Qiu, Junyi6, Wang, Mingchen5, Wei, Fan2,7, Yang, Yaxi1,2,4,5, Zheng, Jie1, Chen, Kaixian1,2, Chen, Shijie1,8, sjchen@pharm.ecnu.edu.cn, Chen, Yi4,7, ychen@simm.ac.cn
Source: Angewandte Chemie; 10/6/2025, Vol. 137 Issue 41, p1-14, 14p
Database: Applied Science & Technology Source
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DbLabel: Applied Science & Technology Source
An: 188493769
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PubType: Academic Journal
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  Data: <searchLink fieldCode="JN" term="%22Angewandte+Chemie%22">Angewandte Chemie</searchLink>; 10/6/2025, Vol. 137 Issue 41, p1-14, 14p
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=aci&AN=188493769
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