PD‐L1 on Tumor‐Derived Extracellular Vesicles Induces CD8+ T Cell Terminal Exhaustion and Mediates Anti‐PD‐1 Resistance in Head and Neck Squamous Cell Carcinoma.

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Title: PD‐L1 on Tumor‐Derived Extracellular Vesicles Induces CD8+ T Cell Terminal Exhaustion and Mediates Anti‐PD‐1 Resistance in Head and Neck Squamous Cell Carcinoma.
Authors: Fang, Ruihua1, Huang, Bixue1, Li, Yun1, Cai, Zhimou1, Deng, Yicheng1, Cen, Xiaoqing1, Sun, Wei1, Zhang, Jinhong1, Xu, Zhenglin1, Guo, Wenbin1, Lyu, Yi1, Luo, Shiyun1, Chen, Zhesheng2, Lyu, Kexing1, lvk5@mail.sysu.edu.cn, Wen, Weiping1, wenwp@mail.sysu.edu.cn, Lei, Wenbin1, leiwb@mail.sysu.edu.cn
Source: Advanced Science; 1/19/2026, Vol. 13 Issue 4, p1-21, 21p
Database: Applied Science & Technology Source
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ISSN:21983844
DOI:10.1002/advs.202516348