Identification of a novel beta-cell glucokinase (GCK) promoter mutation (-71G>C) that modulates GCK gene expression through loss of allele-specific Sp1 binding causing mild fasting hyperglycemia in humans.

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Bibliographic Details
Title: Identification of a novel beta-cell glucokinase (GCK) promoter mutation (-71G>C) that modulates GCK gene expression through loss of allele-specific Sp1 binding causing mild fasting hyperglycemia in humans.
Authors: Gasperíková D (AUTHOR), Tribble ND (AUTHOR), Staník J (AUTHOR), Hucková M (AUTHOR), Misovicová N (AUTHOR), van de Bunt M (AUTHOR), Valentínová L (AUTHOR), Barrow BA (AUTHOR), Barák L (AUTHOR), Dobránsky R (AUTHOR), Bereczková E (AUTHOR), Michálek J (AUTHOR), Wicks K (AUTHOR), Colclough K (AUTHOR), Knight JC (AUTHOR), Ellard S (AUTHOR), Klimes I (AUTHOR), Gloyn AL (AUTHOR), Gasperíková, Daniela1 (AUTHOR), Tribble, Nicolas D (AUTHOR)
Source: Diabetes. Aug2009, Vol. 58 Issue 8, p1929-1935. 7p.
Database: Academic Search Ultimate
Description
ISSN:00121797
DOI:10.2337/db09-0070