58 - TPC-107, a next generation, HER2 selective covalent inhibitor demonstrates potent and sustained inhibition against the HER2–HER3 signaling while sparing EGFR activity, leading to a large therapeutic window.

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Title: 58 - TPC-107, a next generation, HER2 selective covalent inhibitor demonstrates potent and sustained inhibition against the HER2–HER3 signaling while sparing EGFR activity, leading to a large therapeutic window.
Authors: Irie, H., Ito, K., Kataoka, Y., Fujioka, Y., Oguchi, K., Shimamura, T., Kawai, Y., Sagara, T., Shibata, Y., Araki, H., Haruma, T., Hashimoto, A., Matsuo, K., Utsugi, T., Iwasawa, Y.
Source: European Journal of Cancer. Dec2016 Supplement 1, Vol. 69, pS26-S26. 1p.
Database: Academic Search Ultimate
Description
ISSN:09598049
DOI:10.1016/S0959-8049(16)32658-2