ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
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| Title: | ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models. |
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| Authors: | Hanson, Amanda1 (AUTHOR), Elpek, Kutlu1 (AUTHOR), Duong, Ellen1 (AUTHOR), Shallberg, Lindsey1 (AUTHOR), Fan, Martin1 (AUTHOR), Johnson, Calvin1 (AUTHOR), Wallace, Matthew2 (AUTHOR), Mabry, George R.2 (AUTHOR), Sazinsky, Stephen2 (AUTHOR), Pepper, Lauren2 (AUTHOR), Shu, Chengyi J.3 (AUTHOR), Sathyanarayanan, Sriram3 (AUTHOR), Zuerndorfer, Sarah2 (AUTHOR), Simpson, Tyler1 (AUTHOR), Gostissa, Monica4 (AUTHOR), Briskin, Michael5 (AUTHOR), Law, Deborah5 (AUTHOR), Michaelson, Jennifer1 (AUTHOR), Harvey, Christopher J.1 (AUTHOR) charvey@jouncetx.com |
| Source: | PLoS ONE. 9/24/2020, Vol. 15 Issue 9, p1-21. 21p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 19326203 |
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| DOI: | 10.1371/journal.pone.0239595 |
