ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.

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Title: ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
Authors: Hanson, Amanda1 (AUTHOR), Elpek, Kutlu1 (AUTHOR), Duong, Ellen1 (AUTHOR), Shallberg, Lindsey1 (AUTHOR), Fan, Martin1 (AUTHOR), Johnson, Calvin1 (AUTHOR), Wallace, Matthew2 (AUTHOR), Mabry, George R.2 (AUTHOR), Sazinsky, Stephen2 (AUTHOR), Pepper, Lauren2 (AUTHOR), Shu, Chengyi J.3 (AUTHOR), Sathyanarayanan, Sriram3 (AUTHOR), Zuerndorfer, Sarah2 (AUTHOR), Simpson, Tyler1 (AUTHOR), Gostissa, Monica4 (AUTHOR), Briskin, Michael5 (AUTHOR), Law, Deborah5 (AUTHOR), Michaelson, Jennifer1 (AUTHOR), Harvey, Christopher J.1 (AUTHOR) charvey@jouncetx.com
Source: PLoS ONE. 9/24/2020, Vol. 15 Issue 9, p1-21. 21p.
Database: Academic Search Ultimate
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