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First‐in‐human safety, tolerability, and pharmacokinetic results of DFV890, an oral low‐molecular‐weight NLRP3 inhibitor.

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Title: First‐in‐human safety, tolerability, and pharmacokinetic results of DFV890, an oral low‐molecular‐weight NLRP3 inhibitor.
Authors: Gatlik, Ewa1 (AUTHOR), Mehes, Beata1 (AUTHOR), Voltz, Emilie1 (AUTHOR), Sommer, Ulrike1 (AUTHOR), Tritto, Elaine1 (AUTHOR), Lestini, Giulia2 (AUTHOR), Liu, Xiaoxi3 (AUTHOR), Pal, Parasar4 (AUTHOR), Velinova, Maria5 (AUTHOR), Denney, Wiliam S.6 (AUTHOR), Fu, Yunlin3 (AUTHOR), Opipari, Anthony7 (AUTHOR), Dean, Dennis7 (AUTHOR), Junge, Guido1 (AUTHOR) guido.junge@novartis.com
Source: CTS: Clinical & Translational Science. May2024, Vol. 17 Issue 5, p1-16. 16p.
Database: Academic Search Ultimate
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ISSN:17528054
DOI:10.1111/cts.13789