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A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist.

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Title: A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist.
Authors: Le Pen, Jérémie1 (AUTHOR) jlepen@rockefeller.edu, Paniccia, Gabrielle1 (AUTHOR), Kinast, Volker2,3 (AUTHOR), Moncada-Velez, Marcela4 (AUTHOR), Ashbrook, Alison W.1 (AUTHOR), Bauer, Michael1 (AUTHOR), Hoffmann, H.-Heinrich1 (AUTHOR), Pinharanda, Ana5 (AUTHOR), Ricardo-Lax, Inna1 (AUTHOR), Stenzel, Ansgar F.1 (AUTHOR), Rosado-Olivieri, Edwin A.6 (AUTHOR), Dinnon III, Kenneth H.1 (AUTHOR), Doyle, William C.1 (AUTHOR), Freije, Catherine A.1 (AUTHOR), Hong, Seon-Hui1 (AUTHOR), Lee, Danyel4,7,8 (AUTHOR), Lewy, Tyler1 (AUTHOR), Luna, Joseph M.1 (AUTHOR), Peace, Avery1 (AUTHOR), Schmidt, Carltin4 (AUTHOR)
Source: PLoS Biology. 9/24/2024, Vol. 22 Issue 9, p1-49. 49p.
Database: Academic Search Ultimate
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ISSN:15449173
DOI:10.1371/journal.pbio.3002767