A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity.
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| Title: | A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity. |
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| Authors: | Zhang, Da-yan1,2,3 (AUTHOR), Zhang, Zhi-hua1,3 (AUTHOR), Liu, Wen-ting2,3 (AUTHOR), Zhou, Wei-ming2,3 (AUTHOR), Zhou, Peng-fei2,3 (AUTHOR), Wei, Juan-juan2,3 (AUTHOR), Dai, Xue-jing2,3 (AUTHOR), Zeng, Xiao-li2,3 (AUTHOR), Zhou, Yu-qiong2,3 (AUTHOR), Li, Han-wang2,3 (AUTHOR), Zhang, Heng2,3 (AUTHOR), Shen, Ao-lin3,4 (AUTHOR) shenaolin@ustc.edu.cn, Cheng, Lian-sheng2,3 (AUTHOR) charlson@ustc.edu.cn, Shen, Guo-dong3,5 (AUTHOR) gdshen@ustc.edu.cn, He, Yi-fu1,3 (AUTHOR) yifuhe@ffyy.ustc.edu.cn |
| Source: | Journal of Translational Medicine. 1/13/2025, Vol. 23 Issue 1, p1-13. 13p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 14795876 |
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| DOI: | 10.1186/s12967-025-06107-z |
