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A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab.

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Title: A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab.
Authors: Yamada, Akihiro1 (AUTHOR) akihiro.yamada@astellas.com, Choules, Mary P.2 (AUTHOR), Brightman, Frances A.3 (AUTHOR), Takeshita, Shigeru1 (AUTHOR), Nakao, Shinsuke1 (AUTHOR), Amino, Nobuaki1 (AUTHOR), Nakayama, Takeshi1 (AUTHOR), Takeuchi, Masato1 (AUTHOR), Komatsu, Kanji1 (AUTHOR), Ortega, Fernando3 (AUTHOR), Mistry, Hitesh3 (AUTHOR), Orrell, David3 (AUTHOR), Chassagnole, Christophe3 (AUTHOR), Bonate, Peter L.2 (AUTHOR)
Source: CPT: Pharmacometrics & Systems Pharmacology. Mar2025, Vol. 14 Issue 3, p572-582. 11p.
Database: Academic Search Ultimate
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ISSN:21638306
DOI:10.1002/psp4.13297