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Gasdermin-D pores induce an inactivating caspase-4 cleavage that limits IL-18 production in the intestinal epithelium.

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Title: Gasdermin-D pores induce an inactivating caspase-4 cleavage that limits IL-18 production in the intestinal epithelium.
Authors: Bruce, J. K.1,2 (AUTHOR), Li, L. Y.1 (AUTHOR), Tang, Y.3 (AUTHOR), Forster, E. G.3 (AUTHOR), Winsor, N. J.1 (AUTHOR), Bi, P. Y.3 (AUTHOR), Krustev, C.3 (AUTHOR), Keely, S.2 (AUTHOR), Lee, J. E.3 (AUTHOR), Rohde, J. R.4 (AUTHOR), Gaisano, H. Y.5 (AUTHOR), Philpott, D. J.1 (AUTHOR), Girardin, S. E.1,3 (AUTHOR) Stephen.girardin@utoronto.ca
Source: Communications Biology. 5/13/2025, Vol. 8 Issue 1, p1-15. 15p.
Database: Academic Search Ultimate
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ISSN:23993642
DOI:10.1038/s42003-025-08183-9