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NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT.

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Title: NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT.
Authors: Wu, Zheng1 (AUTHOR), Nguyen, Phong T.1 (AUTHOR), Sondhi, Varun1,2 (AUTHOR), Yao, Run-Wen3,4 (AUTHOR), Lu, Zhifang5 (AUTHOR), Dai, Tao1 (AUTHOR), Chiang, Jui-Chung6 (AUTHOR), Cai, Feng1 (AUTHOR), Williams, Imani M.1 (AUTHOR), Blatt, Eliot B.1 (AUTHOR), Shang, Zengfu6 (AUTHOR), Cai, Ling1,7,8 (AUTHOR), Zhang, Jing3,9 (AUTHOR), Moore, Mya D.1 (AUTHOR), Alshamleh, Islam1 (AUTHOR), Li, Xiangyi1 (AUTHOR), Ogu, Tamaratare1 (AUTHOR), Zacharias, Lauren G.1 (AUTHOR), Winston, Rainah1 (AUTHOR), Patricio, Joao S.1 (AUTHOR)
Source: Science. 12/11/2025, Vol. 390 Issue 6778, p1134-1142. 9p.
Database: Academic Search Ultimate
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ISSN:00368075
DOI:10.1126/science.adx9717