Double-CRISPR Knockout Simulation (DKOsim): A Monte-Carlo randomization system to model cell growth behavior and infer the optimal library design for growth-based double knockout screens.
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| Title: | Double-CRISPR Knockout Simulation (DKOsim): A Monte-Carlo randomization system to model cell growth behavior and infer the optimal library design for growth-based double knockout screens. |
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| Authors: | Gu, Yue1,2 (AUTHOR), Hart, Traver3 (AUTHOR), Leon-Novelo, Luis2 (AUTHOR) Jshen8@mdanderson.org, Shen, John Paul1 (AUTHOR) Luis.G.LeonNovelo@uth.tmc.edu |
| Source: | PLoS Computational Biology. 4/17/2026, Vol. 22 Issue 4, p1-27. 27p. |
| Database: | Academic Search Ultimate |
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| ISSN: | 1553734X |
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| DOI: | 10.1371/journal.pcbi.1013510 |