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A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex.

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Title:	A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex.
Authors:	Vuong, Celine K.^1,2,3 (AUTHOR), Weber, Alexis^1,2,3,4,5 (AUTHOR), Seong, Patrick^1,2,3 (AUTHOR), Matoba, Nana^6,7 (AUTHOR), Chen, Yu-Jen^1,2,3 (AUTHOR), Peyer, Jordan^1,2,3,8 (AUTHOR), Younesi, Shahab^1,2,3 (AUTHOR), Salinda, Angelo^1,2,3 (AUTHOR), Gomez, Daniel⁹ (AUTHOR), Rivas, Gabriella⁹ (AUTHOR), Morales, Abril^9,10 (AUTHOR), Shafie, Beck^1,2,3 (AUTHOR), Zhang, Pan^1,2,3 (AUTHOR), Nichterwitz, Susanne^1,2,3 (AUTHOR), Qi, Le^4,11 (AUTHOR), Fernandez, Nolan T.^1,2,3 (AUTHOR), Friedman, Emily^1,2,3 (AUTHOR), Love, Michael I.^6,12 (AUTHOR), Gandal, Michael J.^13,14 (AUTHOR), Geschwind, Daniel H.^1,4,11,15 (AUTHOR)
Source:	Science. 4/23/2026, Vol. 392 Issue 6796, p1-22. 22p.
Database:	Academic Search Ultimate
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ISSN:	00368075
DOI:	10.1126/science.aea1259