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A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex.

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Title: A single-cell multiomic analysis identifies molecular and gene-regulatory mechanisms dysregulated in developing Down syndrome neocortex.
Authors: Vuong, Celine K.1,2,3 (AUTHOR), Weber, Alexis1,2,3,4,5 (AUTHOR), Seong, Patrick1,2,3 (AUTHOR), Matoba, Nana6,7 (AUTHOR), Chen, Yu-Jen1,2,3 (AUTHOR), Peyer, Jordan1,2,3,8 (AUTHOR), Younesi, Shahab1,2,3 (AUTHOR), Salinda, Angelo1,2,3 (AUTHOR), Gomez, Daniel9 (AUTHOR), Rivas, Gabriella9 (AUTHOR), Morales, Abril9,10 (AUTHOR), Shafie, Beck1,2,3 (AUTHOR), Zhang, Pan1,2,3 (AUTHOR), Nichterwitz, Susanne1,2,3 (AUTHOR), Qi, Le4,11 (AUTHOR), Fernandez, Nolan T.1,2,3 (AUTHOR), Friedman, Emily1,2,3 (AUTHOR), Love, Michael I.6,12 (AUTHOR), Gandal, Michael J.13,14 (AUTHOR), Geschwind, Daniel H.1,4,11,15 (AUTHOR)
Source: Science. 4/23/2026, Vol. 392 Issue 6796, p1-22. 22p.
Database: Academic Search Ultimate
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  Data: <searchLink fieldCode="JN" term="%22Science%22">Science</searchLink>. 4/23/2026, Vol. 392 Issue 6796, p1-22. 22p.
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