Comprehensive 4D Parallel Transmission Spatial‐Spectral Pulse Design for Slab‐Selective Uniform Water‐Selective Excitation: Demonstration in the Human Brain at 7 Tesla.
Saved in:
| Title: | Comprehensive 4D Parallel Transmission Spatial‐Spectral Pulse Design for Slab‐Selective Uniform Water‐Selective Excitation: Demonstration in the Human Brain at 7 Tesla. |
|---|---|
| Authors: | Shao, Xin1 (AUTHOR), Zhang, Zhe2 (AUTHOR), Zhong, Wen1 (AUTHOR), Guo, Hua1 (AUTHOR) huaguo@tsinghua.edu.cn, Ugurbil, Kamil3 (AUTHOR), Wu, Xiaoping3 (AUTHOR) |
| Source: | Magnetic Resonance in Medicine. Apr2026, Vol. 95 Issue 4, p2052-2062. 11p. |
| Subjects: | Functional magnetic resonance imaging, Magnetic resonance imaging, Electronic pulse techniques, Diagnostic imaging |
| Abstract: | Purpose: To propose a new parallel transmission (pTx) spatial‐spectral (SPSP) pulse design for achieving slab‐selective uniform water‐selective excitation without unwanted out‐of‐slab fat excitation when using bipolar slab‐selective gradients to maintain a sharp slab profile. Methods: Our new pTx SPSP pulses were designed by formulating the design problem comprehensively in the 4D space (1D spectral and 3D spatial domains) and by incorporating a SPINS‐like 2D excitation k‐space trajectory for within‐slab flip‐angle homogenization. Our new design was validated at 7 T using simulation, phantom and human experiments with the commercial Nova eight‐channel transmit RF head coil. Its utility was demonstrated by comparing to traditional multi‐spoke pTx SPSP pulses. Results: In both simulation and experiments, our design outperformed traditional approaches, producing slab‐selective uniform water‐selective excitation with no out‐of‐slab fat excitation. Quantitatively, coefficient of variation measuring excitation non‐uniformity reduced by up to ∼23%. Conclusion: Our proposed new design provides an effective solution for slab‐selective uniform water‐selective excitation, holding a promise to many applications including mesoscale BOLD fMRI and fat‐free body imaging at ultrahigh field. [ABSTRACT FROM AUTHOR] |
| Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 191184123 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Comprehensive 4D Parallel Transmission Spatial‐Spectral Pulse Design for Slab‐Selective Uniform Water‐Selective Excitation: Demonstration in the Human Brain at 7 Tesla. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Shao%2C+Xin%22">Shao, Xin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Zhe%22">Zhang, Zhe</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhong%2C+Wen%22">Zhong, Wen</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Guo%2C+Hua%22">Guo, Hua</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> huaguo@tsinghua.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Ugurbil%2C+Kamil%22">Ugurbil, Kamil</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wu%2C+Xiaoping%22">Wu, Xiaoping</searchLink><relatesTo>3</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Magnetic+Resonance+in+Medicine%22">Magnetic Resonance in Medicine</searchLink>. Apr2026, Vol. 95 Issue 4, p2052-2062. 11p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Functional+magnetic+resonance+imaging%22">Functional magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Electronic+pulse+techniques%22">Electronic pulse techniques</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnostic+imaging%22">Diagnostic imaging</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: To propose a new parallel transmission (pTx) spatial‐spectral (SPSP) pulse design for achieving slab‐selective uniform water‐selective excitation without unwanted out‐of‐slab fat excitation when using bipolar slab‐selective gradients to maintain a sharp slab profile. Methods: Our new pTx SPSP pulses were designed by formulating the design problem comprehensively in the 4D space (1D spectral and 3D spatial domains) and by incorporating a SPINS‐like 2D excitation k‐space trajectory for within‐slab flip‐angle homogenization. Our new design was validated at 7 T using simulation, phantom and human experiments with the commercial Nova eight‐channel transmit RF head coil. Its utility was demonstrated by comparing to traditional multi‐spoke pTx SPSP pulses. Results: In both simulation and experiments, our design outperformed traditional approaches, producing slab‐selective uniform water‐selective excitation with no out‐of‐slab fat excitation. Quantitatively, coefficient of variation measuring excitation non‐uniformity reduced by up to ∼23%. Conclusion: Our proposed new design provides an effective solution for slab‐selective uniform water‐selective excitation, holding a promise to many applications including mesoscale BOLD fMRI and fat‐free body imaging at ultrahigh field. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=191184123 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mrm.70183 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 11 StartPage: 2052 Subjects: – SubjectFull: Functional magnetic resonance imaging Type: general – SubjectFull: Magnetic resonance imaging Type: general – SubjectFull: Electronic pulse techniques Type: general – SubjectFull: Diagnostic imaging Type: general Titles: – TitleFull: Comprehensive 4D Parallel Transmission Spatial‐Spectral Pulse Design for Slab‐Selective Uniform Water‐Selective Excitation: Demonstration in the Human Brain at 7 Tesla. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Shao, Xin – PersonEntity: Name: NameFull: Zhang, Zhe – PersonEntity: Name: NameFull: Zhong, Wen – PersonEntity: Name: NameFull: Guo, Hua – PersonEntity: Name: NameFull: Ugurbil, Kamil – PersonEntity: Name: NameFull: Wu, Xiaoping IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 07403194 Numbering: – Type: volume Value: 95 – Type: issue Value: 4 Titles: – TitleFull: Magnetic Resonance in Medicine Type: main |
| ResultId | 1 |
