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The Plasma Dose Concept in Plasma Medicine Research: From Physical, Chemical, Biological Parameters to Experimental Methods.

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Title: The Plasma Dose Concept in Plasma Medicine Research: From Physical, Chemical, Biological Parameters to Experimental Methods.
Authors: Pourtalari, Alireza Mohammadian1 (AUTHOR) alirezamp56@gmail.com
Source: High Energy Chemistry. Jun2026, Vol. 60 Issue 3, p410-421. 12p.
Subjects: Chemical properties, Plasma diagnostics, Therapeutics, Chemical reactions, Medical technology, Physical constants, Empirical research
Abstract: Plasma dose is one of the central challenges in plasma medicine. Understanding the concept of dose in plasma medicine is a key issue for the safe and effective use of this technology. Unlike drugs or ionizing radiation, dose in plasma medicine is not a simple, single quantity, but rather a combined parameter. Plasma dose is usually defined by a combination of physical and chemical parameters. These parameters are related to the way the plasma is applied, its energy, and the biologically active agents. Challenges in determining the optimal and effective dose arise from the lack of a universal standard unit. An effective dose may produce completely different biological effects with different gases (Helium or Argon) because the chemical composition of the plasma changes. For example, the effective dose to kill cancer cells is much different than the dose used to heal diabetic wounds or regenerate cells. For the future clinical use of plasma medicine, the development of devices that can deliver the "dose" accurately is an absolute necessity. This article attempts to address the complexities of defining dose in plasma medicine. To this end, the main components of plasma dose, the parameters affecting it, and the common units for expressing plasma dose in current research trends are carefully reported. [ABSTRACT FROM AUTHOR]
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Database: Engineering Source
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Abstract:Plasma dose is one of the central challenges in plasma medicine. Understanding the concept of dose in plasma medicine is a key issue for the safe and effective use of this technology. Unlike drugs or ionizing radiation, dose in plasma medicine is not a simple, single quantity, but rather a combined parameter. Plasma dose is usually defined by a combination of physical and chemical parameters. These parameters are related to the way the plasma is applied, its energy, and the biologically active agents. Challenges in determining the optimal and effective dose arise from the lack of a universal standard unit. An effective dose may produce completely different biological effects with different gases (Helium or Argon) because the chemical composition of the plasma changes. For example, the effective dose to kill cancer cells is much different than the dose used to heal diabetic wounds or regenerate cells. For the future clinical use of plasma medicine, the development of devices that can deliver the "dose" accurately is an absolute necessity. This article attempts to address the complexities of defining dose in plasma medicine. To this end, the main components of plasma dose, the parameters affecting it, and the common units for expressing plasma dose in current research trends are carefully reported. [ABSTRACT FROM AUTHOR]
ISSN:00181439
DOI:10.1134/S0018143925601915