An efficient method for synthesis of α-keto acid esters from terminal alkynes

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Bibliographic Details
Title: An efficient method for synthesis of α-keto acid esters from terminal alkynes
Authors: Li, Lian-Sheng1, Wu, Yu-Lin ylwu@pub.sioc.ac.cn
Source: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Mar2002, Vol. 43 Issue 13, p2427. 4p.
Subjects: Esters, Ketonic acids, Bromination
Abstract: α-Keto acid esters can be easily prepared in high yields in two steps from terminal alkynes via bromination and oxidation. This strategy provides a versatile access to the synthesis of biologically important natural products with an α-keto acid moiety. [Copyright &y& Elsevier]
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Database: Engineering Source
Description
Abstract:α-Keto acid esters can be easily prepared in high yields in two steps from terminal alkynes via bromination and oxidation. This strategy provides a versatile access to the synthesis of biologically important natural products with an α-keto acid moiety. [Copyright &y& Elsevier]
ISSN:00404039
DOI:10.1016/S0040-4039(02)00290-3